Morbidity after inguinal sentinel lymph node biopsy and completion lymph node dissection in patients with cutaneous melanoma
Morbidity after inguinal sentinel lymph node biopsy and completion lymph node dissection in patients with cutaneous melanoma
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DOI：
10.1016/j.ejso.2006.05.003
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发表时间：
2006-09-01
期刊：
影响因子：
3.8
通讯作者：
Hoekstra, H. J.
中科院分区：
文献类型：
--
作者：
de Vries, M.;Vonkeman, W. G.;Hoekstra, H. J.
背景资料：本研究的目的是评估短期和长期发病率腹股沟前哨淋巴结活检（SLNB）或不完成腹股沟清扫（GD）皮肤melanoma.Methods患者：1995年至2003年，127腹股沟SLNB进行皮肤黑色素瘤。66例患者，中位年龄50（18-77）岁，符合入选标准，并进行了研究。短期并发症进行了回顾性分析，而长期并发症进行了评估，使用体积测量和活动范围测量的下肢.Results：52例患者进行了SLNB单独（SLNB组）和14例患者进行了完整的腹股沟解剖后肿瘤阳性SLNB（SLNB/GD组）。单独SLNB后的死亡率：伤口感染（n = 1）、阴囊（n = 1）、术后出血（n = 1）、丹毒（n = 1）和轻度水肿6%（n = 3）。SLNB/GD后死亡率：伤口感染（n = 4）、血清肿（17 = 1）、伤口坏死（n = 1）、术后出血（n = 1）和轻度水肿64%（n = 9）。两组在近期并发症总数（p < 0.001）、髋关节体积差（p < 0.001）、髋关节屈曲（p = 0.009）和髋关节外展（p = 0.011）受限方面存在差异。然而，SLNB后腹股沟夹层与伤口感染和轻微水肿的风险增加相关。(c)2006爱思唯尔有限公司保留所有权利。
Background: Aim of the study was to assess the short-term and long-term morbidity after inguinal sentinel lymph node biopsy (SLNB) with or without completion groin dissection (GD) in patients with cutaneous melanoma.Methods: Between 1995 and 2003, 127 inguinal SLNBs were performed for cutaneous melanoma. Sixty-six patients, median age 50 (18-77) years, met the inclusion criteria and were studied. Short-term complications were analysed retrospectively, while long-term complications were evaluated using volume measurement and range of motion measurement of the lower extremities.Results: Fifty-two patients underwent SLNB alone (SLNB group) and 14 patients underwent completion groin dissection after tumour-positive SLNB (SLNB/GD group). Morbidity after SLNB alone: wound infections (n = 1), scroma (n = 1), postoperative bleeding (n = 1), erysipelas (n = 1), and slight lymphedema 6% (n = 3). Morbidity after SLNB/GD: wound infections (n = 4), seroma (17 = 1), wound necrosis (n = 1), postoperative bleeding (n = 1), and slight lymphedema 64% (n = 9). There were differences between the two groups in the total number of short-term complications (p < 0.001), volume difference (p < 0.001), flexion (p = 0.009), and abduction (p = 0.011) limitation of the hip joint.Conclusion: Inguinal SLNB is accompanied with a low complication rate. However, SLNB followed by groin dissection is associated with an increased risk of wound infection and slight lymphedema. (c) 2006 Elsevier Ltd. All rights reserved.