Uterine NK cell education: Learning the ropes in pregnancy.
Uterine NK cell education: Learning the ropes in pregnancy.
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子宫 NK 细胞教育：学习怀孕期间的诀窍。
DOI：
10.1016/j.immuni.2021.05.009
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发表时间：
2021
期刊：
影响因子：
32.4
通讯作者：
Coyne,CarolynB
中科院分区：
文献类型：
--
作者：
Wells,AlexandraI;Coyne,CarolynB
抑制性受体NKG2A介导的教育对子宫NK（uNK）细胞对血管重塑的反应性对妊娠结局的影响尚不清楚。在这一期的《免疫》中，Shreeve et al.显示NKG2A+uNK细胞的损失导致血管形成不足和胎儿生长受限。
The impact of inhibitory receptor NKG2A-mediated education on uterine NK (uNK) cell responsiveness to vascular remodeling on pregnancy outcomes has remained unclear. In this issue ofImmunity, Shreeve et al. show that loss of NKG2A+uNK cells results in deficient vascularization and restricted fetal growth.