Photodynamic antitumor activity of aggregation-induced emission luminogens as chemosensitizers for paclitaxel by concurrent induction of apoptosis and autophagic cell death
Photodynamic antitumor activity of aggregation-induced emission luminogens as chemosensitizers for paclitaxel by concurrent induction of apoptosis and autophagic cell death
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聚集诱导发射发光剂作为紫杉醇化学增敏剂通过同时诱导细胞凋亡和自噬细胞死亡的光动力抗肿瘤活性
DOI：
10.1039/d1qm00089f
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发表时间：
2021-02-27
影响因子：
7
通讯作者：
Xu, Huae
中科院分区：
文献类型：
--
作者：
Wang, Jia;Zhang, Wenling;Xu, Huae
TPE-Py通过诱导肿瘤细胞凋亡和自噬性死亡抑制肿瘤细胞生长，白色光照射可增强TPE-Py抑制肿瘤细胞生长的作用。TPE-Py通过白色光照射诱导细胞凋亡来增强Ptx的抗癌活性。
TPE-Py inhibits the growth of tumor cells by inducing apoptotic and autophagic cell death, and the effect could be enhanced by white light irradiation. TPE-Py enhances the anticancer activity of Ptx by inducing apoptosis by white light irradiation.