Comparison of pesticides and other compounds in carpet dust samples collected from used vacuum cleaner bags and from a high-volume surface sampler
Comparison of pesticides and other compounds in carpet dust samples collected from used vacuum cleaner bags and from a high-volume surface sampler
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DOI：
10.2307/3434260
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发表时间：
1998-11-01
影响因子：
10.4
通讯作者：
Hartge, P
中科院分区：
文献类型：
--
作者：
Colt, JS;Zahm, SH;Hartge, P
对居民使用农药与癌症风险之间关系的流行病学研究需要对过去的农药暴露进行评估。地毯灰尘中的农药含量被认为反映了长期使用农药的情况。最近的流行病学研究发现，使用大容量表面采样器（HVS 3）收集灰尘样本是昂贵和繁琐的。我们比较了从受试者个人使用的真空吸尘器袋中获得的灰尘中的农药和其他化合物的水平与HVS 3收集的灰尘，看看这种更简单的方法是否可以在流行病学研究中取代HVS 3。我们访问了15名受试者的家中，从他们的真空吸尘器中取出用过的袋子，并用HVS 3收集地毯灰尘样本。采用GC/MS选择离子监测模式，对26种农药、10种多环芳烃（PAHs）和6种多氯联苯（PCB）等42种目标化合物进行了分析。这两种方法在80%和100%的时间内检测到目标化合物的存在。这两种取样方法都不总是更敏感。中位目标化合物浓度相似，配对t检验显示无显著差异。对于许多化合物，在浓度范围的上限，HVS 3样品中的化合物浓度高于所用袋样品中的化合物浓度。然而，大多数化合物的斯皮尔曼等级相关系数为0.85或更高，表明使用这两种方法对房屋进行相似的排名。总体而言，两种粉尘收集方法的农药、多环芳烃或多氯联苯浓度数据的质量似乎没有明显差异。
Epidemiologic studies of the association between residential pesticide use and cancer risk require an assessment of past pesticide exposures. Pesticide levels in carpet dust are believed to reflect long-term pesticide use. Recent epidemiologic studies have found collection of dust samples using the high-volume surface sampler (HVS3) to be expensive and cumbersome. We compared the levels of pesticides and other compounds in dust obtained from subjects' personal used vacuum cleaner bags to that collected by the HVS3 to see if this simpler method could replace the HVS3 in epidemiologic research. We visited the homes of 15 subjects, took the used bags from their vacuums, and collected carpet dust samples with the HVS3. The samples were analyzed for 42 target compounds: 26 pesticides, 10 polycyclic aromatic hydrocarbons (PAHs), and six polychlorinated biphenyl (PCB) congeners using GC/MS in selected ion monitoring mode. The two methods agreed in detecting the presence of the target compounds between 80% and 100% of the time. Neither sampling method was consistently more sensitive. The median target compound concentrations were similar, and a paired t-test showed no significant differences. For many compounds, the concentrations of compounds in the HVS3 samples were higher than those in the used bag samples at the upper end of the concentration ranges. However, the Spearman rank correlation coefficients were 0.85 or higher for most compounds, indicating that homes would be ranked similarly using both methods. Overall, there appears to be no clear difference in the quality of the pesticide, PAH, or PCB concentration data for the two dust collection methods.