Utility of CT scan evaluation for predicting pulmonary hypertension in patients with parenchymal lung disease
Utility of CT scan evaluation for predicting pulmonary hypertension in patients with parenchymal lung disease
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DOI：
10.1378/chest.113.5.1250
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发表时间：
1998-05-01
期刊：
影响因子：
9.6
通讯作者：
Presberg, KW
中科院分区：
文献类型：
--
作者：
Tan, RT;Kuzo, R;Presberg, KW
目的：确定CT确定的主肺动脉直径（MPAD）预测肺实质性肺疾病患者肺动脉高压（PH）的实用性。设计：回顾性分析45例患者的右心血流动力学数据和胸部CT扫描。设置：三级转诊教学医院和VA医院。患者：在1990年10月至1995年12月期间，36名因实质性肺疾病或可能的肺血管疾病而转诊的患者被发现患有PH，定义为平均肺动脉压（mPAP）大于或等于20 mm Hg。9名对照患者（mPAP 1：1，在三个或四个叶（特异性，100%）。结论：CT检查MPAD对晚期肺疾病患者PR的诊断有较高的价值。因此，标准胸部CT扫描可用于筛查肺实质性肺病患者劳力受限的原因。由于CT通常用于评估肺实质疾病，因此该信息很容易获得。
Objective: To determine the utility of CT-determined main pulmonary artery diameter (MPAD) for predicting pulmonary hypertension (PH) in patients with parenchymal lung disease.Design: Retrospective review of right-heart hemodynamic data and chest CT scans in 45 patients.Setting: Tertiary-referral teaching hospital and VA hospital.Patients: Between October 1990 and December 1995, 36 patients referred for evaluation of parenchymal lung disease or possible pulmonary vascular disease were found to have PH, as defined by mean pulmonary artery pressure (mPAP) greater than or equal to 20 mm Hg. Nine control patients (mPAP 1:1 in three or four lobes (specificity, 100%). There was no linear correlation between the degree of PH and MPAD (r=0.124).Conclusions: CT-determined MPAD has excellent diagnostic value for detection of PR in patients with advanced lung disease. Therefore, standard chest CT scans can be used to screen for PH as a cause of exertional limitation in patients with parenchymal lung disease. Because CT is commonly used to evaluate parenchymal lung disease, this information is readily available.