Knowledge, attitude, and perception regarding HPV-related diseases and vaccination among the general public in Guizhou Province of China.
Knowledge, attitude, and perception regarding HPV-related diseases and vaccination among the general public in Guizhou Province of China.
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DOI：
10.1016/j.vaccine.2022.12.027
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发表时间：
2023-01
期刊：
影响因子：
5.5
通讯作者：
Luhong Xie;J. Ren;Shao-ju Min;Xiao-Jin Zhu;Dianqin Xu;Kun Qiao;Xiaowei Chen;Min Liu;Zi-wen Xiao;Yujie Tan
中科院分区：
文献类型：
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作者：
Luhong Xie;J. Ren;Shao-ju Min;Xiao-Jin Zhu;Dianqin Xu;Kun Qiao;Xiaowei Chen;Min Liu;Zi-wen Xiao;Yujie Tan
在中国，高危人乳头瘤病毒（HR-HPV）型相关疾病的患病率不断上升，对健康构成了持续的挑战。在本研究中，我们评估了贵州省公众目前对HPV和HPV疫苗接种的看法，为未来在该地区推广HPV疫苗接种的方向提供建议。方法采用在线问卷调查方法，对贵州省本地成年居民3412人（女性2532人，男性880人）进行调查。收集了有关社会人口统计学特征、HPV知识和HPV疫苗接种观念的数据。在学生和非学生之间以及有和没有医学背景的参与者之间进行了数据比较。所有统计分析均使用SPSS 26.0进行。结果自报HPV感染率女性为5.85%，男性为0.86%。46.29%的女性和34.43%的男性对HPV知识达到可接受水平，47.54%的女性对HPV疫苗知识达到可接受水平。非学生和医学参与者在知识测试中的表现明显好于他们各自的对立组。网络媒体是所有参与者中最受欢迎的HPV信息来源。93.58%的女性和87.88%的男性表示愿意接种HPV疫苗。接受疫苗接种的主要促进因素是女性（OR = 1.932, 95% CI: 1.390-2.685,p< 0.001）或学生（OR = 2.276, 95% CI: 1.206 - 4.291,p= 0.011），以及HPV知识水平较高的参与者（OR = 1.796, 95% CI: 1.300-2.481,p< 0.001）。年龄41-50岁（OR = 0.255, 95% CI: 0.121-0.538,p= 0.001）或bbb50岁（OR = 0.141, 95% CI: 0.059-0.337,p< 0.001）是对HPV疫苗接种持否定态度的显著预测因子。结论贵州居民对hpv相关问题的了解程度较低。达到可接受知识水平的卫生保健工作者的百分比为一半或更少。如果研制出价格更合理的疫苗，并消除年轻人和医务人员普遍知识水平低的问题，就可以控制人乳头瘤病毒流行率和宫颈癌发病率的上升。
BackgroundThe rising prevalence of high-risk human papillomavirus (HR-HPV) type-related diseases pose an ongoing health challenge in China. In this study, we assessed the current views of the general public of the Guizhou Province on HPV and HPV vaccinations to provide recommendations for future directions regarding the rollout of HPV vaccination in the area.MethodsAn online questionnaire survey was conducted that included 3412 (2532 females and 880 males) native adult residents of the Guizhou Province. Data on the socio-demographic characteristics, knowledge of HPV, and perceptions of HPV vaccinations were collected. Data comparisons were made between students and non-students and between participants with and without medical backgrounds. All statistical analyses were performed using SPSS 26.0.ResultsThe self-reported HPV infection rates were 5.85% in women and 0.86% in men. A total of 46.29% of women and 34.43% of men achieved acceptable knowledge levels of HPV and 47.54% of women possessed an acceptable knowledge level of HPV vaccines. Non-students and medical participants performed significantly better in the knowledge tests than their respective opposing groups. Online media was the most popular HPV information source for all the participants. A total of 93.58% of women and 87.88% of men expressed willingness toward HPV vaccination. The major facilitators of vaccination acceptance were females (OR = 1.932, 95% CI: 1.390–2.685,p< 0.001) or students (OR = 2.276, 95% CI: 1.207–4.291,p= 0.011), and participants with higher HPV knowledge level (OR = 1.796, 95% CI: 1.300–2.481,p< 0.001). Ages 41–50 (OR = 0.255, 95% CI: 0.121–0.538,p= 0.001) or > 50 (OR = 0.141, 95% CI: 0.059–0.337,p< 0.001) were significant predictors of a negative attitude towards HPV vaccination.ConclusionGuizhou residents had poor knowledge of HPV-related issues. The percentage of healthcare workers who achieved acceptable knowledge levels was one-half or less. The increasing HPV prevalence and cervical cancer incidence can be contained if more affordable vaccines are developed and the low knowledge levels pervading young adults and medical staff is eliminated.