Multiecho IDEAL Gradient-Echo Water-Fat Separation for Rapid Assessment of Cartilage Volume at 1.5 T: Initial Experience

Multiecho IDEAL Gradient-Echo Water-Fat Separation for Rapid Assessment of Cartilage Volume at 1.5 T: Initial Experience
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DOI:
10.1148/radiol.2522081424
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发表时间:
2009-08-01
期刊:
影响因子:
19.7
通讯作者:
Gold, Garry E.
Gold, Garry E.
中科院分区:
医学1区
文献类型:
--
作者:
Chen, Christina A.;Lu, Wenmiao;Gold, Garry E.

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这项符合 HIPAA 标准的研究已获得机构审查委员会的批准和知情同意。目的是前瞻性地将水和脂肪的多回波迭代分解与回波不对称和最小二乘估计 (IDEAL) 梯度回波 (GRE) 磁共振 (MR) 成像与三维脂肪抑制 (FS) 损坏的 GRE (SPGR) MR 成像进行比较,以评估膝关节软骨。在 1.5 T 下对 6 名健康志愿者和 10 具尸体膝盖进行成像。测量了信噪比 (SNR)、SNR 效率和软骨体积。多回波 IDEAL GRE 的 SNR 和 SNR 效率显着高于 FS SPGR 成像 (P < .031)。两种方法都产生了同等的软骨体积(总体一致性相关系数为 0.998),且具有高精度和准确度。软骨模型的使用证实了两种方法体积测量的高精度和高再现性。多回波 IDEAL GRE 在软骨和滑液中提供高信号强度,是一种有前景的膝关节软骨成像技术。 (c) 北美放射学会,2009 年
Institutional review board approval and informed consent were obtained for this HIPAA-compliant study. The purpose was to prospectively compare multiecho iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) gradient-echo (GRE) magnetic resonance (MR) imaging with three-dimensional fat-suppressed (FS) spoiled GRE (SPGR) MR imaging to evaluate the articular cartilage of the knee. Six healthy volunteer and 10 cadaver knees were imaged at 1.5 T. Signal-to-noise ratio (SNR), SNR efficiency, and cartilage volume were measured. SNR and SNR efficiency were significantly higher with multiecho IDEAL GRE than with FS SPGR imaging (P < .031). Both methods produced equivalent cartilage volumes (overall concordance correlation coefficient, 0.998) with high precision and accuracy. The use of a cartilage phantom confirmed high accuracy in volume measurements and high reproducibility for both methods. Multiecho IDEAL GRE provides high signal intensity in cartilage and synovial fluid and is a promising technique for imaging articular cartilage of the knee. (c) RSNA, 2009