Complex regional pain syndrome type I: incidence and prevalence in Olmsted county, a population-based study
Complex regional pain syndrome type I: incidence and prevalence in Olmsted county, a population-based study
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DOI：
10.1016/s0304-3959(03)00065-4
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发表时间：
2003-05-01
期刊：
影响因子：
7.4
通讯作者：
Low, PA
中科院分区：
文献类型：
--
作者：
Sandroni, P;Benrud-Larson, LM;Low, PA
本研究的目的是对复杂性区域疼痛综合征(CRPS)的发病率、患病率、自然病史和治疗反应进行一项基于人群的研究。作为罗切斯特流行病学项目的一部分，对1989-1999年期间所有梅奥诊所和奥姆斯特德医疗集团的带有反射性交感神经营养不良(RSD)、CRPS和兼容诊断代码的医疗记录进行了审查。我们对CRPS采用了IASP标准。研究人群在明尼苏达州的奥姆斯特德县(1990年人口，106,470人)。主要观察指标为CRPS I发病率、患病率和预后。确诊了74例CRPS I病例，发病率为5.46/10万人年，患病率为20.57/10万人年。男女之比为4：1，发病年龄中位数为46岁。上肢受累的几率是下肢的两倍。所有病例都报告了先天事件，骨折是最常见的触发因素(46%)。症状和体征之间有很好的一致性，最常见的是血管舒缩症状。三期骨扫描和自主神经测试在80%的病例中诊断出这种情况。70%的患者接受了解决，通常是自发的。CRPS I的患病率较低，女性比男性更常见，上肢多于下肢，四分之三的病例得到了解决。这些结果表明，在大多数病例中，CRPS的侵入性治疗可能是不必要的。(C)2003年国际疼痛研究协会。爱思唯尔科学公司出版。版权所有。
The objective of this study is to undertake a population based study on the incidence, prevalence, natural history, and response to treatment of complex regional pain syndrome (CRPS). All Mayo Clinic and Olmsted Medical Group medical records with codes for reflex sympathetic dystrophy (RSD), CRPS, and compatible diagnoses in the period 1989-1999 were reviewed as part of the Rochester Epidemiology Project. We used IASP criteria for CRPS. The study population was in the Olmsted County, Minnesota (1990 population, 106,470). The main outcome measures were CRPS I incidence, prevalence, and outcome. Seventy-four cases of CRPS I were identified, resulting in an incidence rate of 5.46 per 100,000 person years at risk, and a period prevalence of 20.57 per 100,000. Female:male ratio was 4: 1, with a median age of 46 years at onset. Upper limb was affected twice as commonly as lower limb. All cases reported an antecedent event and fracture was the most common trigger (46%). Excellent concordance was found between symptoms and signs and vasomotor symptoms were the most commonly present. Three phase bone scan and autonomic testing diagnosed the condition in >80% of cases. Seventy-foar percent of patients underwent resolution, often spontaneously. CRPS I is of low prevalence, more commonly affects women than men, the upper more than the lower extremity, and three out of four cases undergo resolution. These results suggest that invasive treatment of CRPS may not be warranted in the majority of cases. (C) 2003 International Association for the Study of Pain. Published by Elsevier Science B.V. All rights reserved.