Salivary diagnostics
Salivary diagnostics
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DOI：
10.1511/2008.69.3669
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发表时间：
2008-01-01
影响因子：
--
通讯作者：
Wong, David T.
中科院分区：
文献类型：
--
作者：
Wong, David T.
唾液从一个人的嘴变成了最近最有价值的样本检测疾病和人体的生理状态。使用唾液样本的主要优点是其容易获得，成本效益高，而且它不会使卫生保健工作者暴露于血液传播疾病。对唾液中存在的各种蛋白质的研究可以帮助检测简单到复杂的疾病，如干燥综合征，胰腺癌，乳腺癌和口腔癌。鉴定唾液中的糖蛋白，沿着不同的RNA和mRNA，它们存在于唾液的无细胞部分中，可以帮助检测疾病阶段。使用唾液进行检测的另一个优点是，唾液中的细胞外蛋白比血浆中更丰富。
Salivary from a person's mouth is turning out to be the recent most valuable sample for detection of diseases and the physiological state of the human body. The main advantages of using salivary sample is its easy availability, cost effectiveness and the fact that it doesn't expose health care workers to blood-borne diseases. A study of various proteins present in saliva can help detect simple to complex diseases like Sjogren's syndrome, pancreatic cancer, breast cancer and oral cancer. Identifications of glycoproteins in saliva, along with the different RNAs and mRNA, which are present in the cell-free portion of saliva, can help in detecting the diseased stage. Another advantage of using saliva for detection is that extracellular proteins are more abundant in the saliva than plasma.