Molecular Phylogeny of Heme Peroxidases
Molecular Phylogeny of Heme Peroxidases
复制标题
血红素过氧化物酶的分子系统发育
DOI：
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发表时间：
2010
期刊：
影响因子：
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通讯作者：
C. Obinger
中科院分区：
文献类型：
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作者：
C. Obinger
所有现有的血红素过氧化物酶基因序列可以在遗传学上分为两个超家族和三个家族。在本章中，每个群体的遗传学和基因组分布。在过氧化物酶-环氧合酶超家族中，主要的进化方向是开发参与先天免疫防御系统和（碘化）激素生物合成的过氧化物血红素蛋白。过氧化物酶-过氧化氢酶超家族主要在细菌、真菌和植物中广泛分布，特别是在I类中导致了双功能过氧化氢酶-过氧化物酶的进化。它的许多第二类真菌代表参与通过木质素降解的碳循环，而来自藻类和植物的第三类分泌性过氧化物酶包括在各种形式的次生代谢中。二血红素过氧化物酶家族主要是细菌诱导的酶;然而，在古细菌基因组中也检测到一些相应的基因。dyp-type过氧化物酶主要存在于细菌中，有四个亚家族，它们能降解各种外源性物质
All currently available gene sequences of heme peroxidases can be phylogenetically divided in two superfamilies and three families. In this chapter, the phylogenetics and genomic distribution of each group are presented. Within the peroxidase-cyclooxygenase superfamily, the main evolutionary direction devel- oped peroxidatic heme proteins involved in the innate immune defense system and in biosynthesis of (iodinated) hormones. The peroxidase-catalase superfamily is widely spread mainly among bacteria, fungi, and plants, and particularly in Class I led to the evolution of bifunctional catalase-peroxidases. Its numerous fungal representatives of Class II are involved in carbon recycling via lignin degradation, whereas Class III secretory peroxidases from algae and plants are included in various forms of secondary metabolism. The family of di-heme peroxidases are predominantly bacteria-inducible enzymes; however, a few corresponding genes were also detected in archaeal genomes. Four subfamilies of dyp-type peroxidases capable of degradation of various xenobiotics are abundant mainly among bacteria
影响因子：
2.9
作者：
Wang, YT;Graichen, ME;Davidson, VL
通讯作者：
Davidson, VL
影响因子：
7.4
作者：
Cheng, Guangjie;Salerno, John C.;Cao, Zehong;Pagano, Patrick J.;Lambeth, J. David
通讯作者：
Lambeth, J. David