Quality of pediatric clinical practice guidelines.
Quality of pediatric clinical practice guidelines.
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DOI：
10.1186/s12887-021-02693-1
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发表时间：
2021-05-07
期刊：
影响因子：
2.4
通讯作者：
Ma Y
中科院分区：
文献类型：
--
作者：
Liu Y;Zhang Y;Wang S;Liu L;Che G;Niu J;Ma Y
近年来，儿科临床实践指南（CPG）缺乏全面的评价。在这里，我们评估了儿科CPG的质量，考虑可能影响其质量的因素。研究的目的是促进更一致的CPGs的开发和应用。检索并收集了2017年至2019年期间在PubMed、MedLive、国际指南网络、国家健康与护理卓越研究所和世界卫生组织发表的儿科CPG。配对的研究人员进行筛选，数据提取和质量评估使用的研究和评估指南II（AGREE II）的评价。线性回归分析确定了影响CPG质量的因素。该研究共纳入216例CPG，在AGREE II评估中平均得分为4.26分（7分）（60.86%）。只有6.48%的CPG达到“推荐”水平。其余69.91%在推荐前就应该修改，而另外23.61%根本没有达到推荐水平。近期儿科CPG的总体质量高于以前，低质量CPG的比例随着时间的推移而下降。但是，达到高质量水平的CPG还是太少了。“适用性”和“开发的严谨性”领域的得分普遍较低。由发展中国家或地区制定的CPG，那些不属于组织或团体的责任，以及那些使用非循证方法的CPG被认为是与不同领域的质量较差相关的独立或组合因素。儿科CPG的质量仍需提高。具体而言，在应用新的CPG之前进行质量控制对于确保其质量和适用性至关重要。在线版本包含补充材料，可通过10.1186/s12887-021-02693-1获得。
There is a lack of a comprehensive evaluation for pediatric clinical practice guidelines (CPGs) published in recent years. Here, we assessed the quality of pediatric CPGs, considering factors that might affect their quality. The aim of the study is to promote a more coherent development and application of CPGs. Pediatric CPGs published in PubMed, MedLive, Guidelines International Network, National Institute for Health and Care Excellence, and World Health Organization between 2017 and 2019 were searched and collected. Paired researchers conducted screening, data extraction, and quality assessment using the Appraisal of Guidelines for Research and Evaluation II (AGREE II). Linear regression analysis determined the factors affecting CPGs’ quality. The study included a total of 216 CPGs, which achieved a mean score of 4.26 out of 7 points (60.86%) in the AGREE II assessment. Only 6.48% of the CPGs reached the “recommend” level. The remaining 69.91% should have been modified before recommendation, while the other 23.61% did not reach the recommended level at all. The overall quality of recent pediatric CPGs was higher than previously, and the proportion of CPGs with low-quality decreased over time. However, there were still too few CPGs that reached a high-quality level. The “applicability” and “rigor of development” domains had generally low scores. CPGs formulated by developing countries or regions, those that are not under an organizations or groups responsibility, and those that used non-evidence-based methods were found to be associated with poorer quality in different domains as independent or combinational factors. The quality of pediatric CPGs still needs to be improved. Specifically, a quality control before applying new CPGs should be essential to ensure their quality and applicability. The online version contains supplementary material available at 10.1186/s12887-021-02693-1.
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