Hepatic hemangioendothelioma of infancy: treatment with interferon alpha.
Hepatic hemangioendothelioma of infancy: treatment with interferon alpha.
复制标题
婴儿期肝血管内皮瘤：干扰素α治疗。
DOI：
10.1097/00005176-199703000-00019
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发表时间：
1997
影响因子：
2.9
通讯作者：
Egeler Rm
中科院分区：
文献类型：
--
作者：
Woltering Mc;S. Robben;Egeler Rm
血管瘤和血管内皮瘤实际上是毛细血管的增生而不是血管畸形。由于高流量，血管扩张。血管瘤是婴儿期最常见的血管疾病。它们是出生后不久出现的小而无害的胎记，在最初的8-18个月内扩大，然后在5-8年内慢慢消失。它们有时可能危及生命，特别是当它们涉及喉，parthelyheal区域或重要结构，如心脏，纵隔和肝脏时（15）。相比之下，婴儿期肝血管内皮瘤是一种不同的病理实体，其特征是多灶性良性血管病变，通常累及肝脏和皮肤（16）。
DISCUSSIONHemangiomas and hemangioendotheliomas are in fact proliferations of capillaries rather than vascular malformations. The vessels are dilated as a consequence of the high flow. Hemangiomas are the most common vascular disorders of infancy. They are small, harmless birthmarks that appear soon after birth, enlarge in the first 8-18 months, and then involute slowly in 5-8 years. They sometimes can be life-threatening, especially when they involve the larynx, paratracheal regions, or vital structures such as the heart, mediastinum, and liver (15). By contrast, the hepatic hemangioendothelioma of infancy is a different pathologic entity, characterized by multifocal benign vascular lesions, typically involving both the liver and skin (16).