Destruction of RhoA CULtivates actin.
Destruction of RhoA CULtivates actin.
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DOI:
10.1016/j.molcel.2009.09.012
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发表时间:
2009-09-24
期刊:
影响因子:
16
通讯作者:
Wolf, Dieter A.
中科院分区:
文献类型:
--
作者:
Wu, Shuangding;Wolf, Dieter A.
Cullin 3, the core subunit of the CRL3 ubiquitin ligase family, is essential for development, but its substrates remain poorly defined. Here, report that CRL3BACURD targets the RhoA GTPase for degradation thereby maintaining actin cytoskeleton integrity.
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