Regulation of clock genes.
Regulation of clock genes.
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时钟基因的调节。
DOI：
10.1007/s000180050366
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发表时间：
1999
期刊：
影响因子：
--
通讯作者：
Dunlap,JC
中科院分区：
文献类型：
--
作者：
Liu,Y;Heintzen,C;Loros,J;Dunlap,JC
最近，对蓝细菌、真菌、昆虫、哺乳动物以及植物中潜在候选生物钟成分的鉴定出现了爆炸式增长，发现了这些成分的结构、功能和调节之间的共同主题。人们发现，负反馈回路中组织的正负相互作用对于时钟功能至关重要。转录和转录后机制似乎对于所有这些生物体的昼夜节律产生都很重要。
A recent explosion in the identification of new clock components in cyanobacteria, fungi, insects, mammals as well as potential candidates in plants has uncovered common themes among the structure, function and regulation of these components. Positive and negative interactions that are organized in negative feedback loops have been found crucial for clock function. Both transcriptional and posttranscriptional mechanisms appear to be important for circadian rhythm generation in all of these organisms.