babA2- and cagA-positive Helicobacter pylori strains are associated with duodenal ulcer and gastric carcinoma in Brazil
babA2- and cagA-positive Helicobacter pylori strains are associated with duodenal ulcer and gastric carcinoma in Brazil
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DOI：
10.1128/jcm.41.8.3964-3966.2003
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发表时间：
2003-08-01
影响因子：
9.4
通讯作者：
Queiroz, DMM
中科院分区：
文献类型：
--
作者：
Oliveira, AG;Santos, A;Queiroz, DMM
对208株巴西幽门螺杆菌的babA2和cagA基因进行了研究。babA2与十二指肠溃疡或胃癌之间存在很强的相关性，即使在调整了混杂因素（如年龄、性别和cagA状态）后也是如此。caga阳性菌株也与幽门螺杆菌相关疾病独立相关。
The babA2 and cagA genes were investigated in 208 Brazilian Helicobacter pylori strains. A strong association between babA2 and duodenal ulcer or gastric carcinoma was observed, even after adjusting for confounding factors, such as age, gender, and cagA status. cagA-positive strains were also independently associated with H. pylori-related diseases.