US Valuation of Health Outcomes Measured Using the PROMIS-29
US Valuation of Health Outcomes Measured Using the PROMIS-29
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DOI：
10.1016/j.jval.2014.09.005
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发表时间：
2014-12-01
期刊：
影响因子：
4.5
通讯作者：
Revicki, Dennis A.
中科院分区：
文献类型：
--
作者：
Craig, Benjamin M.;Reeve, Bryce B.;Revicki, Dennis A.
目的：健康评估研究通过评估健康相关生活质量（HRQOL）的价值来加强治疗的经济评估。患者报告结局测量信息系统（PROMIS）包括29项简短HRQOL测量，PROMIS-29。研究方法：为了评估PROMIS-29的质量调整生命年规模的反应，我们进行了一项全国性调查（N = 7557），使用基于美国2010年人口普查的配额抽样。基于541个配对比较，每个配对比较超过350个响应，将配对特异性概率纳入加权最小二乘估计。结果如下：HRQOL的所有损失影响选择;然而，受访者重视身体功能，焦虑，抑郁，睡眠和疼痛的损失超过疲劳和社会功能。结论：本文介绍了一种新的方法来评估HRQOL的经济评价使用配对比较，并提供了一个工具，转换PROMIS-29的反应到质量调整生命年。
Objectives: Health valuation studies enhance economic evaluations of treatments by estimating the value of health-related quality of life (HRQOL). The Patient-Reported Outcomes Measurement Information System (PROMIS) includes a 29-item short-form HRQOL measure, the PROMIS-29. Methods: To value PROMIS-29 responses on a quality-adjusted life year scale, we conducted a national survey (N = 7557) using quota sampling based on the US 2010 Census. Based on 541 paired comparisons with over 350 responses each, pair-specific probabilities were incorporated into a weighted least-squared estimator. Results: All losses in HRQOL influenced choice; however, respondents valued losses in physical function, anxiety, depression, sleep, and pain more than those in fatigue and social functioning. Conclusions: this article introduces a novel approach to valuing HRQOL for economic evaluations using paired comparisons and provides a tool to translate PROMIS-29 responses into quality-adjusted life-years.