The emotional brain: Fundamental questions and strategies for future research

The emotional brain: Fundamental questions and strategies for future research
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DOI:
10.1016/j.neulet.2018.10.012
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发表时间:
2019-02-06
影响因子:
2.5
通讯作者:
Wager, Tor D.
Wager, Tor D.
中科院分区:
医学4区
文献类型:
--
作者:
Shackman, Alexander J.;Wager, Tor D.

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情绪在人类体验中扮演着核心角色。随着时间的推移,操纵情绪的方法变得越来越精致,理解潜在神经生物学的技术变得更加强大和精确,使人们能够对大脑中情绪的组织有新的见解。然而,近年来,关于情绪的本质和起源的辩论异常激烈,知名科学家对过去25年来激励和指导该领域的事实和原则的规范提出了令人信服的担忧。在这里,我们考虑最近的神经成像研究如何为这种对话提供信息。通过将注意力集中在关于情感本质和情感大脑结构的最重要的悬而未决的问题上,我们希望刺激推动该领域向前发展所需的各种工作。解决这些问题是至关重要的,不仅对于理解心灵,而且对于阐明其许多疾病的根本原因。
Emotions play a central role in human experience. Over time, methods for manipulating emotion have become increasingly refined and techniques for making sense of the underlying neurobiology have become ever more powerful and precise, enabling new insights into the organization of emotions in the brain. Yet recent years have witnessed a remarkably vigorous debate about the nature and origins of emotion, with leading scientists raising compelling concerns about the canon of facts and principles that has inspired and guided the field for the past quarter century. Here, we consider ways in which recent neuroimaging research informs this dialogue. By focusing attention on the most important outstanding questions about the nature of emotion and the architecture of the emotional brain, we hope to stimulate the kinds of work that will be required to move the field forward. Addressing these questions is critical, not just for understanding the mind, but also for elucidating the root causes of many of its disorders.