Breast US computer-aided diagnosis system: robustness across urban populations in South Korea and the United States.
Breast US computer-aided diagnosis system: robustness across urban populations in South Korea and the United States.
复制标题
美国乳房计算机辅助诊断系统：韩国和美国城市人口的稳健性。
DOI：
10.1148/radiol.2533090280
复制
发表时间：
2009
期刊：
影响因子：
19.7
通讯作者：
Pesce,LorenzoL
中科院分区：
文献类型：
--
作者：
Gruszauskas,NicholasP;Drukker,Karen;Giger,MaryellenL;Chang,Ruey-Feng;Sennett,CharleneA;Moon,WooKyung;Pesce,LorenzoL
PurposeTo evaluate the robustness of a breast ultrasonographic (US) computer-aided diagnosis (CAD) system in terms of its performance across different patient populations.Materials and MethodsThree US databases were analyzed for this study: one South Korean and two United States databases. All three databases were utilized in an institutional review board–approved and HIPAA-compliant manner. Round-robin analysis and independent testing were performed to evaluate the performance of a computerized breast cancer classification scheme across the databases. Receiver operating characteristic (ROC) analysis was used to evaluate performance differences.ResultsThe round-robin analyses of each database demonstrated similar results, with areas under the ROC curve ranging from 0.88 (95% confidence interval [CI]: 0.820, 0.918) to 0.91 (95% CI: 0.86, 0.95). The independent testing of each database, however, indicated that although the performances were similar, the range in areas under the ROC curve (from 0.79 [95% CI: 0.730, 0.842] to 0.87 [95% CI: 0.794, 0.923]) was wider than that with the round-robin tests. However, the only instances in which statistically significant differences in performance were demonstrated occurred when the Korean database was used in a testing capacity in independent testing.ConclusionThe few observed statistically significant differences in performance indicated that while the US features used by the system were useful across the databases, their relative importance differed. In practice, this means that a CAD system may need to be adjusted when applied to a different population.© RSNA, 2009
