A checklist for retrospective database studies - Report of the ISPOR task force on retrospective databases
A checklist for retrospective database studies - Report of the ISPOR task force on retrospective databases
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DOI：
10.1046/j.1524-4733.2003.00242.x
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发表时间：
2003-03-01
期刊：
影响因子：
4.5
通讯作者：
Stang, P
中科院分区：
文献类型：
--
作者：
Motheral, B;Brooks, J;Stang, P
引言：健康相关的回顾性数据库，特别是索赔数据库，仍然是结局研究的重要数据来源。然而，回顾性数据库提出了一系列的方法上的挑战，其中一些是独特的本datasource.Methods：在努力帮助决策者在评估使用健康相关的回顾性数据库发表的研究的质量，一个清单的开发，重点是数据库研究的独特问题或数据库研究中特别有问题。这份清单主要是为常用的医疗索赔或基于数据库，但可能会被用来评估采用其他类型的数据库，如疾病登记和国家调查data.Results的回顾性研究：书面形式的27个问题，清单可以用来指导决策者，因为他们认为数据库，研究方法，和研究结论。检查表的问题涵盖了广泛的问题，包括相关性，可靠性和有效性，数据链接，资格确定，研究设计，治疗效果，样本选择，审查，变量定义，资源评估，统计分析，概括性，和数据interpretation.Conclusions：对于许多问题，关键参考资料提供的资源，为那些谁想要进一步研究一个特定的问题。
Introduction: Health-related retrospective databases, in particular claims databases, continue to be an important data source for outcomes research. However, retrospective databases pose a series of methodological challenges, some of which are unique to this data source.Methods: In an effort to assist decision makers in evaluating the quality of published studies that use health-related retrospective databases, a checklist was developed that focuses on issues that are unique to database studies or are particularly problematic in database research. This checklist was developed primarily for the commonly used medical claims or encounter-based databases but could potentially be used to assess retrospective studies that employ other types of databases, such as disease registries and national survey data.Results: Written in the form of 27 questions, the checklist can be used to guide decision makers as they consider the database, the study methodology, and the study conclusions. Checklist questions cover a wide range of issues, including relevance, reliability and validity, data linkages, eligibility determination, research design, treatment effects, sample selection, censoring, variable definitions, resource valuation, statistical analysis, generalizability, and data interpretation.Conclusions: For many of the questions, key references are provided as a resource for those who want to further examine a particular issue.