Prospective diagnosis of the initial prodrome for schizophrenia based on the structured interview for prodromal syndromes: Preliminary evidence of interrater reliability and predictive validity
Prospective diagnosis of the initial prodrome for schizophrenia based on the structured interview for prodromal syndromes: Preliminary evidence of interrater reliability and predictive validity
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DOI：
10.1176/appi.ajp.159.5.863
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发表时间：
2002-05-01
影响因子：
17.7
通讯作者：
Woods, SW
中科院分区：
文献类型：
--
作者：
Miller, TJ;McGlashan, TH;Woods, SW
目的：本研究旨在确定一套基于前驱症状结构化访谈的精神分裂症精神病首发前驱症状诊断标准的判读信度和预测效度。方法：研究对象为疑似精神分裂症前驱综合征的患者。在可靠性研究中，两到四名评分员在面对面或录像访谈的基础上独立诊断了18名患者。对于有效性研究，收集了29例患者6个月和12个月的结果数据。结果：前驱与非前驱的鉴别符合率为93%。46%的前驱症状患者在6个月时转化为精神分裂症，54%在12个月时转化为精神分裂症。结论：在小群体的受试者中，这些精神分裂症前驱症状的诊断标准和前驱症状的结构化访谈显示出良好的判读信度和预测效度。
objective: This study was conducted to determine the interrater reliability and predictive validity of a set of diagnostic criteria for the prodrome of the first episode of schizophrenic psychosis when based on the Structured Interview for Prodromal Syndromes.Method: The subjects were patients referred for evaluation because of a suspected schizophrenia prodromal syndrome. For the reliability study, two to four raters independently diagnosed 18 patients on the basis of face-to-face or videotaped interviews. For the validity study, 6- and 12-month outcome data were collected for 29 patients.Results: Agreement in differentiating prodromal from nonprodromal patients was 93%. The prodromal features had converted to schizophrenic psychosis for 46% of the prodromal patients at 6 months and for 54% at 12 months.Conclusions: In small groups of subjects, these diagnostic criteria for the schizophrenic prodrome and the Structured Interview for Prodromal Syndromes showed promising interrater reliability and predictive validity.