The synchronicity of COVID-19 disparities: Statewide epidemiologic trends in SARS-CoV-2 morbidity, hospitalization, and mortality among racial minorities and in rural America.
The synchronicity of COVID-19 disparities: Statewide epidemiologic trends in SARS-CoV-2 morbidity, hospitalization, and mortality among racial minorities and in rural America.
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DOI：
10.1371/journal.pone.0255063
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发表时间：
2021
期刊：
影响因子：
3.7
通讯作者：
Embi PJ
中科院分区：
文献类型：
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作者：
Dixon BE;Grannis SJ;Lembcke LR;Valvi N;Roberts AR;Embi PJ
关于 COVID-19 的早期研究发现，城市环境中少数种族和族裔的住院治疗和死亡率存在不平等模式。这些研究主要是在大流行的最初几周或几个月内进行的单中心观察研究。我们试图研究少数族裔和农村人口随着时间的推移，特别是在美国秋季高峰期间，COVID-19 发病率、住院率和死亡率的趋势。数据是从 2020 年 3 月 1 日至 12 月 31 日期间对印第安纳州所有成年居民进行 SARS-CoV-2 感染检测的全州范围中提取的，并与电子健康记录相关联。主要衡量指标是人均感染率、住院率和死亡率。根据公共卫生缓解措施，计算了多个时间段的年龄调整率。使用方差分析来比较组内不同时间的比较。发病率和死亡率随着时间的推移而增加，亚人群之间存在显着差异。最初，少数族裔的住院率是白人的3-4倍，城市居民的死亡率是农村居民的两倍。到 2020 年秋季，农村地区的住院率和死亡率超过城市地区，黑人/棕色人种与白人人口之间的差距缩小。人口群体之间随时间的变化对发病率和住院率有显着影响。少数民族群体和农村社区的累计发病率和死亡率最高。 COVID-19 的种族和地理差异的同步性表明，卫生官员应明确衡量差异并调整缓解措施以及疫苗接种策略，以保护那些疾病负担较重的亚人群。
Early studies on COVID-19 identified unequal patterns in hospitalization and mortality in urban environments for racial and ethnic minorities. These studies were primarily single center observational studies conducted within the first few weeks or months of the pandemic. We sought to examine trends in COVID-19 morbidity, hospitalization, and mortality over time for minority and rural populations, especially during the U.S. fall surge. Data were extracted from a statewide cohort of all adult residents in Indiana tested for SARS-CoV-2 infection between March 1 and December 31, 2020, linked to electronic health records. Primary measures were per capita rates of infection, hospitalization, and death. Age adjusted rates were calculated for multiple time periods corresponding to public health mitigation efforts. Comparisons across time within groups were compared using ANOVA. Morbidity and mortality increased over time with notable differences among sub-populations. Initially, hospitalization rates among racial minorities were 3–4 times higher than whites, and mortality rates among urban residents were twice those of rural residents. By fall 2020, hospitalization and mortality rates in rural areas surpassed those of urban areas, and gaps between black/brown and white populations narrowed. Changes across time among demographic groups was significant for morbidity and hospitalization. Cumulative morbidity and mortality were highest among minority groups and in rural communities. The synchronicity of disparities in COVID-19 by race and geography suggests that health officials should explicitly measure disparities and adjust mitigation as well as vaccination strategies to protect those sub-populations with greater disease burden.
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影响因子：
4.9
作者：
Peters, David J.
通讯作者：
Peters, David J.
影响因子：
4.9
作者：
Kaufman, Brystana G.;Whitaker, Rebecca;Holmes, G. Mark
通讯作者：
Holmes, G. Mark
影响因子：
3.8
作者：
Blonde L;Khunti K;Harris SB;Meizinger C;Skolnik NS
通讯作者：
Skolnik NS
影响因子：
4.9
作者：
Karim, Saleema A.;Chen, Hsueh-Fen
通讯作者：
Chen, Hsueh-Fen
DOI：
10.15585/mmwr.mm6946a6
发表时间：
2020-11-20
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
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作者：
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