Current concepts. II. New evidence for a locus coeruleus-norepinephrine connection with anxiety.

Current concepts. II. New evidence for a locus coeruleus-norepinephrine connection with anxiety.
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DOI:
10.1016/0024-3205(79)90087-0
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发表时间:
1979
期刊:
影响因子:
6.1
通讯作者:
Y. Huang
Y. Huang
中科院分区:
医学2区
文献类型:
--
作者:
D. Redmond;Y. Huang

文献摘要

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综述了脑去甲肾上腺素能系统具有广泛的生物学功能的假说,该假说与人类的恐惧或焦虑有关。在最近的解剖学、生理学、药理学和动物行为学实验的背景下,提出了非人灵长类动物蓝斑核功能研究的数据。建议对焦虑、药物成瘾、疼痛和心身疾病的治疗有启示。
The hypothesis that brain noradrenergic systems have a broad biological function which is related to human fear or anxiety is reviewed. Data from studies of the function of the nucleus locus coereleus in non-human primates are presented in the context of recent anatomical, physiological, pharmacological, and animal behavioral experiments. Implications are suggested for the treatment of anxiety, drug addictions, pain, and psychosomatic diseases.