Comparison of blood viscosity using a torsional oscillation viscometer and a rheometer.
Comparison of blood viscosity using a torsional oscillation viscometer and a rheometer.
复制标题
使用扭转振荡粘度计和流变仪比较血液粘度。
DOI：
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发表时间：
2008
影响因子：
2.1
通讯作者：
S. Forconi
中科院分区：
文献类型：
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作者：
V. Travagli;I. Zanardi;L. Boschi;A. Gabbrielli;V. Mastronuzzi;R. Cappelli;S. Forconi
缺乏一个简单的和临床实用的方法来确定全血粘度可以部分证明为什么医学界一直缓慢认识到全血粘度的意义。出于这个原因，能够以快速和直接的方式评估血液粘度的技术的可用性是受欢迎的。为了评价一种新型扭振式粘度计在血液流变学实验室中的可行性，将其与传统的锥板系统进行了比较。粘度比较与盐水溶液中全血和悬浮血的红细胞压积值相关。结果表明，新设备具有良好的重复性和再现性，红细胞压积0-100%范围内的最佳拟合数据由决定系数表征，r2>0.95。此外，对从住院患者采集的血液样本进行了两种仪器测量的全血粘度比较。在两种方法之间发现粘度值的合理一致性，其中两种测量方法之间的线性决定系数在r2=0.7329和0.9263之间，这取决于剪切应力相和相应的剪切速率。
The absence of a simple and clinically practical method to determine whole blood viscosity can partly justify why the medical community has been slow in realizing the significance of whole blood viscosity. For this reason, the availability of a technique able to evaluate blood viscosity in a rapid and direct manner is welcome. To evaluate the feasibility in hemorheological laboratory of a new torsional oscillation viscometer, it was compared with a conventional cone-plate system. The viscosity comparison has been related to hematocrit value both on whole blood and suspended blood in a saline solution. The results showed a good repeatability and reproducibility of the new equipment, with a best-fitting data of the hematocrit 0-100% range characterized by coefficient of determinations, r2>0.95. Furthermore, a comparison of whole blood viscosity as measured by the two instruments was done on blood samples collected from hospitalized patients. Reasonable agreement for the viscosity values was found between the two methods with linear determination coefficients between the two measurement methods comprised between r2=0.7329 and 0.9263, depending on shear stress phase and the corresponding shear rate.