AMYOPATHIC DERMATOMYOSITIS - A REVIEW

AMYOPATHIC DERMATOMYOSITIS - A REVIEW
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DOI:
10.1038/jid.1993.35
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发表时间:
1993-01-01
影响因子:
6.5
通讯作者:
SONTHEIMER, RD
SONTHEIMER, RD
中科院分区:
医学1区
文献类型:
--
作者:
EUWER, RL;SONTHEIMER, RD

文献摘要

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Jim Gilliam的研究兴趣在他的整个职业生涯中被迫更好地定义风湿性疾病的皮肤和全身表现之间存在的关系。尽管他的大部分时间都花在研究红斑狼疮患者的这种关系上,但他在这方面也对皮肌炎(DM)非常感兴趣。他对这种偶尔发生的疾病的皮肤和肌肉表现的分离特别感兴趣。术语“无症状性肌炎”过去被用于描述仅表现为DM皮肤表现的患者;然而,很少有来自此类患者系统检查的已发表数据。出于几个原因,我们更喜欢术语“无肌病性皮肌炎”来描述罕见的患者,他们长时间患有糖尿病的经典皮肤病变,作为其疾病的唯一临床显著表现。在本报告中,我们回顾了我们自己的个人经验,一组六个这样的病人,并比较和对比,
Jim Gilliam's research interests throughout his career were forced upon better defining the relationships that exist between the cutaneous and systemic manifestations of the rheumatic diseases. Although the majority of his time was spent studying such relationships in lupus erythematosus patients, he was also intensely interested in dermatomyositis (DM) in this regard as well. He was particularly intrigued with the dissociation of the cutaneous and muscular manifestations of this disorder that occasionally occurs. The term ''demiatomyositis sine myositis'' has been used in the past to describe patients who present with only the cutaneous manifestations of DM; however, very little published data is available from systematic examinations of such patients. For several reasons, we have preferred the term ''amyopathic dermatomyositis'' to describe that rare patient who for long periods of time suffers from the classical skin lesions of DM as the only clinically significant manifestation of their disease. In this presentation, we review our own personal experience with a group of six such patients and compare and contrast it to that