Impact of 4D image quality on the accuracy of target definition
Impact of 4D image quality on the accuracy of target definition
复制标题
4D图像质量对目标定义精度的影响
DOI：
--
复制
发表时间：
2015
影响因子：
--
通讯作者：
C. Brink
中科院分区：
文献类型：
--
作者：
T. Nielsen;C. Hansen;J. Westberg;O. Hansen;C. Brink
目标形状和位置的勾画精度取决于图像质量。这项研究调查了标准4D系统上的图像质量是否具有可与总体描绘不确定性相媲美的影响。在三种不同的4D计算机断层扫描(CT)系统和4D锥束CT(CBCT)系统上，使用动态胸部模型，使用预先定义的临床扫描方案，对运动的肺目标进行成像。使用刚性配准和自动勾画分别配准峰间运动和靶区体积。计算了成像不确定度的空间分布，即成像目标与真实目标形状之间的距离偏差。测量到的运动小于实际运动。不同呼吸时相间成像靶区的体积存在差异。在运动方向上测量了>；0.4厘米的成像不确定度，这表明成像的目标形状有很大的变形。标准4D系统的成像不确定度与典型的GTV-CTV扩展(0.5-1厘米)的大小相似，并且对目标清晰度的不确定度有相当大的影响。建议对4D系统进行优化和验证，以获得最佳成像目标形状。
Delineation accuracy of target shape and position depends on the image quality. This study investigates whether the image quality on standard 4D systems has an influence comparable to the overall delineation uncertainty. A moving lung target was imaged using a dynamic thorax phantom on three different 4D computed tomography (CT) systems and a 4D cone beam CT (CBCT) system using pre-defined clinical scanning protocols. Peak-to-peak motion and target volume were registered using rigid registration and automatic delineation, respectively. A spatial distribution of the imaging uncertainty was calculated as the distance deviation between the imaged target and the true target shape. The measured motions were smaller than actual motions. There were volume differences of the imaged target between respiration phases. Imaging uncertainties of >0.4 cm were measured in the motion direction which showed that there was a large distortion of the imaged target shape. Imaging uncertainties of standard 4D systems are of similar size as typical GTV–CTV expansions (0.5–1 cm) and contribute considerably to the target definition uncertainty. Optimising and validating 4D systems is recommended in order to obtain the most optimal imaged target shape.
影响因子：
3.8
作者：
Ford, EC;Mageras, GS;Ling, CC
通讯作者：
Ling, CC
影响因子：
3.8
作者：
Pevsner, A;Davis, B;Mageras, GS
通讯作者：
Mageras, GS
DOI：
10.1016/j.ijrobp.2008.05.008
发表时间：
2008-09-01
影响因子：
7
作者：
Wang, He;Adam, S. Garden;Zhang, Lifei;Wei, Xiong;Ahamad, Anesa;Kuban, Deborah A.;Komaki, Ritsuko;O'Daniel, Jennifer;Zhang, Yongbin;Mohan, Radhe;Dong, Lei
通讯作者：
Dong, Lei