Stimulating bioelectronic medicine discovery for urological disorders.
Stimulating bioelectronic medicine discovery for urological disorders.
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促进泌尿系统疾病的生物电子医学发现。
DOI：
10.1152/ajprenal.00372.2017
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
Osborne,PeregrineB
中科院分区：
文献类型：
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作者：
Osborne,PeregrineB
这个颠覆性技术的时代是否会为泌尿系统和肾脏相关疾病的治疗带来新的机会？如果最近政府和私人对生物电子医学的重大投资是任何指标的话，这似乎是可能的。在一系列公私合作的倡议之后，对生物电子医学的兴趣迅速增长，这表明葛兰素史克打算开发“电刺激”，可以改变生物刺激设备作为治疗方法的使用（2）。美国政府机构随后在这一新兴领域进行了进一步的重大投资（13）。其中一个来源是美国国防高级研究计划局（DARPA），但可能与泌尿和肾脏相关疾病更相关的是美国国立卫生研究院（NIH）共同基金计划刺激外周活动以缓解疾病（NIH），该计划专门针对器官功能障碍的生物电子医学研究。国家糖尿病、消化和肾脏疾病研究所（NIDDK）是与NIH主任办公室合作开展该项目的四个研究所之一（https：//commonfund. nih。gov/sparc）。
will this era of disruptive technologies bring new opportunities for treating urological and kidney-related disorders? This seems likely if recent major government and private investments in bioelectronic medicines are any indicator.Interest in bioelectronic medicine has grown rapidly following a series of public-private initiatives which signaled the intention of GlaxoSmithKline to develop “electroceuticals” that could transform the use of biological stimulation devices as therapeutics (2). Further significant investments in this emerging field were then made by US government agencies (13). One source has been the Defense Advanced Research Projects Agency (DARPA), but possibly more relevant to urological and kidney-related disorders is the National Institutes of Health (NIH) Common Fund program Stimulating Peripheral Activity to Relieve Conditions (SPARC), which is specifically targeting bioelectronic medicine research to organ dysfunction. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is one of four Institutes working in partnership with the NIH Office of the Director on this program (https://commonfund. nih. gov/sparc).