Is it traffic type, volume, or distance? Wheezing in infants living near truck and bus traffic

Is it traffic type, volume, or distance? Wheezing in infants living near truck and bus traffic
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DOI:
10.1016/j.jaci.2005.05.014
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发表时间:
2005-08-01
影响因子:
14.2
通讯作者:
Lockey, J
Lockey, J
中科院分区:
医学1区
文献类型:
--
作者:
Ryan, PH;LeMasters, G;Lockey, J

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目的:我们试图确定交通类型、交通流量和距离与1岁以下婴儿喘息之间的关系。方法:开发地理信息系统和分类方案,将参加研究的婴儿分为居住在行驶中的卡车和公共汽车交通(高速公路50英里/小时,每天1000辆卡车,400米)、走走停停的卡车和公共汽车交通(<时速50英里,100米),或者没有暴露,不在附近居住。症状数据基于婴儿6个月大时对父母进行的健康问卷调查和每月的健康日记。结果:与未接触过的婴儿相比,生活在公交车和卡车交通非常近(<100 m)的婴儿喘息的发生率显著增加(调整后的优势比为2.50;95%可信区间为1.15-5.42)。无论暴露在何种环境中,非白人婴儿的喘息率至少是白人婴儿的两倍。然而,居住在距离高交通流量400m以内的婴儿并没有增加喘息的患病率。结论:这些结果表明,与交通流量相比,距离交通暴露的距离和类型是婴儿早期喘息的更显著的危险因素。
Background: Previous studies of air pollution have not examined the association between exposure to varying types, distance, and amounts of traffic and wheezing in very young infants.Objective: We sought to determine the relationship between types of traffic, traffic volume, and distance and wheezing among infants less than 1 year of age.Methods: A geographic information system and a classification scheme were developed to categorize infants enrolled in the study as living near moving truck and bus traffic (highway > 50 miles per hour, > 1000 trucks daily, < 400 m), stop-and-go truck and bus traffic (< 50 miles per hour, < 100 m), or unexposed and not residing near either. Symptom data were based on health questionnaires administered to parents when the infants were 6 months of age and monthly health diaries.Results: Infants living very near (< 100 m) stop-and-go bus and truck traffic had a significantly increased prevalence of wheezing (adjusted odds ratio, 2.50; 95% CI, 1.15-5.42) when compared with unexposed infants. The prevalence of wheezing among nonwhite infants was at least twice that of white infants, regardless of exposure. Infants living less than 400 m from a high volume of moving traffic, however, did not have an increased prevalence of wheezing.Conclusion: These results suggest that the distance from and type of traffic exposures are more significant risk factors than traffic volume for wheezing in early infancy.