Support for Establishing Best Practices for Breastfeeding in the Current HIV/ART Era.
Support for Establishing Best Practices for Breastfeeding in the Current HIV/ART Era.
复制标题
支持在当前艾滋病毒/抗逆转录病毒治疗时代建立母乳喂养最佳实践。
DOI：
10.1093/jpids/piab128
复制
发表时间：
2022
影响因子：
3.2
通讯作者：
Chahroudi,Ann
中科院分区：
文献类型：
--
作者：
Cranmer,LisaM;Chung,MichaelH;Chahroudi,Ann
传染病学会的Yusuf等人描述了一项支持在约翰霍普金斯医院选择母乳喂养的艾滋病毒感染妇女的倡议。作者成功地开发和实施了一个全面的危害减少方案，以响应最近的变化，卫生和人类服务部（DHHS）围产期艾滋病毒指南。Yusuf等人在美国首次报道了10名出生时感染WLHIV的婴儿孕前开始抗逆转录病毒治疗（ART）的结果数据。在母乳喂养4.4个月后，没有人感染艾滋病毒。越来越多的证据表明，在整个怀孕和哺乳期间接受抗逆转录病毒治疗并持续抑制病毒的母亲中，母乳喂养期间的产后艾滋病毒传播极为罕见。在接受抗逆转录病毒治疗的母乳喂养WLHIV的4项研究（N= 2392）中，6个月时婴儿艾滋病毒的总体传播率为0.37%(95% CI 0.17%-0.71%)，而所有研究均为0.37%
Infectious Diseases Society, Yusuf et al describe an initiative to support women living with HIV (WLHIV) who chose to breastfeed at Johns Hopkins Hospital. The authors successfully developed and implemented a comprehensive harm reduction program in response to recent changes in Department of Health and Human Services (DHHS) perinatal HIV guidelines. Yusuf et al are the first to report outcome data in the United States of 10 infants born to WLHIV who started antiretroviral therapy (ART) preconception. None acquired HIV infection after breastfeeding for a median duration of 4.4 months.There is a growing body of evidence to suggest that postnatal HIV transmission during breastfeeding is exceedingly rare among mothers who maintain sustained viral suppression while on ART throughout pregnancy and breastfeeding. Among 4 studies of breastfeeding WLHIV on ART (N= 2392), overall infant HIV transmission at 6 months was 0.37%(95% CI 0.17%-0.71%), and all