Negative Self-Referential Processing Predicts the Recurrence of Major Depressive Episodes.
Negative Self-Referential Processing Predicts the Recurrence of Major Depressive Episodes.
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DOI：
10.1177/2167702616654898
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发表时间：
2017-01
期刊：
影响因子：
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通讯作者：
Gotlib IH
中科院分区：
文献类型：
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作者：
LeMoult J;Kircanski K;Prasad G;Gotlib IH
大多数患有重度抑郁症（MDD）的人都会经历复发性抑郁发作;然而，我们对增加复发可能性的认知机制知之甚少。在目前的研究中，我们研究了是否负偏自我参照处理，负性生活事件，基线抑郁症状，精神药物的使用预测随后的抑郁发作的发作在一个纵向研究的女性复发性抑郁症的历史。基线水平较高的抑郁症状预示着经历更多的负面生活事件，反过来，这往往预示着抑郁症的复发。重要的是，在考虑了其他相关因素后，负偏差的自我参照处理对未来三年内经历抑郁发作的可能性贡献了独特的方差。因此，负偏的自我参照处理似乎是抑郁发作复发的一个重要风险因素，并可能是旨在预防未来发作的干预措施的一个重要目标。
Most individuals who develop Major Depressive Disorder (MDD) will experience a recurrent depressive episode; we know little, however, about cognitive mechanisms that increase the likelihood of recurrence. In the current study we examined whether negatively biased self-referential processing, negative life events, baseline depressive symptoms, and psychotropic medication use predicted the onset of a subsequent depressive episode in a longitudinal study of women with a history of recurrent MDD. Higher levels of depressive symptoms at baseline predicted experiencing a greater number of negative life events which, in turn, tended to predict recurrence of depression. Importantly, after accounting for other associations, negatively biased self-referential processing contributed unique variance to the likelihood of experiencing a depressive episode over the next three years. Thus, negatively biased self-referential processing appears to be a significant risk factor for the recurrence of depressive episodes and may be an important target for interventions aimed at preventing future episodes.