Occupational Exposures and Hodgkin Lymphoma: Canadian Case-Control Study
Occupational Exposures and Hodgkin Lymphoma: Canadian Case-Control Study
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DOI：
10.1097/jom.0b013e3181be6bfe
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发表时间：
2009-12-01
影响因子：
3.2
通讯作者：
Pahwa, Punam
中科院分区：
文献类型：
--
作者：
Karunanayake, Chandima P.;Singh, Gayatri V.;Pahwa, Punam
目的：目的是研究霍奇金淋巴瘤（HL）与加拿大男性长期职业相关的职业暴露之间的关系。方法：以人群为基础，按居住省份和年龄组对男性进行HL病例对照研究。采用条件逻辑回归对统计模型进行拟合。结果：几个独立因素增加了HL的风险曾经暴露于铀的电离辐射显示与HL有显著关联吸烟25年或以上的男性最有可能患HL暴露于紫外线和诊断为麻疹与HL呈负相关，而诊断为带状疱疹则增加了HL的风险。结论：患HL的高风险可能与暴露于铀电离辐射和吸烟年数有关。[J] .中华医学杂志，2009;51:1447-1454。
Objective: The objective was to study the association between Hodgkin Lymphoma (HL) and occupational exposures related to long-held occupation among males in Canada. Methods: A population-based case-control study of HL was conducted among males stratified by Province of residence and age group. Conditional logistic regression was used to fit statistical models. Results: Several factors independently increased the risk of HL Ever exposure to ionizing radiation from uranium showed a significant association with HL Men who had smoked cigarettes for 25 years or more were the most likely to develop HL Exposure to ultraviolet light and diagnosis with measles were negatively associated with HL, whereas diagnosis with shingles increased the risk of HL. Conclusions: The higher risk of developing HL may be associated with exposure to uranium ionizing radiation and years of cigarette smoking. (J Occup Environ Med. 2009;51:1447-1454)