Tissue Blood Flow During Remifentanil Infusion With Carbon Dioxide Loading.
Tissue Blood Flow During Remifentanil Infusion With Carbon Dioxide Loading.
复制标题
二氧化碳负荷瑞芬太尼输注期间的组织血流。
作者：
Hiroaki Kanbe;N. Matsuura;Masataka Kasahara;T. Ichinohe
本研究旨在探讨瑞芬太尼（Remi）输注过程中呼气末二氧化碳分压（ETCO 2）的变化对家兔口腔组织血流的影响。在机械通气下，用七氟烷麻醉8只气管切开的雄性日本白色家兔。雷米的输注速率为0.4 μg/kg/min。在吸入气体中加入二氧化碳以改变吸入CO2张力，以防止通气条件的变化。观察变量为收缩压（SBP）、舒张压（DBP）、平均动脉压（MAP）、心率（HR）、颈总动脉血流量（CCBF）、舌粘膜血流量（TBF）、下颌骨骨髓组织血流量（BBF）、咬肌组织血流量（MBF）、上牙槽组织血流量（UBF）和下牙槽组织血流量（LBF）。高碳酸血症时，CCBF、TBF、BBF、UBF和LBF值增加，而MBF值减少，反之亦然。在雷米输注期间，高碳酸血症下BBF、UBF和LBF值增加，而MBF值降低，反之亦然。在Remi输注期间，BBF、MBF、UBF和LBF值（而非CCBF和TBF值）随ETCO 2变化而沿着变化。
The aim of this study was to investigate the effect of changes in end-tidal carbon dioxide tension (ETCO2) during remifentanil (Remi) infusion on oral tissue blood flow in rabbits. Eight male tracheotomized Japan White rabbits were anesthetized with sevoflurane under mechanical ventilation. The infusion rate of Remi was 0.4 μg/kg/min. Carbon dioxide was added to the inspired gas to change the inspired CO2 tension to prevent changes in the ventilating condition. Observed variables were systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), common carotid artery blood flow (CCBF), tongue mucosal blood flow (TBF), mandibular bone marrow tissue blood flow (BBF), masseter muscle tissue blood flow (MBF), upper alveolar tissue blood flow (UBF), and lower alveolar tissue blood flow (LBF). The CCBF, TBF, BBF, UBF, and LBF values were increased, while MBF was decreased, under hypercapnia, and vice versa. The BBF, UBF, and LBF values were increased, while the MBF value was decreased, under hypercapnia during Remi infusion, and vice versa. The BBF, MBF, UBF, and LBF values, but not the CCBF and TBF values, changed along with ETCO2 changes during Remi infusion.
高碳酸血症和缺氧高碳酸血症期间的区域静脉流出量、血容量和交感神经活动。
影响因子：
2.1
作者：
Hoka,S;Arimura,H;Bosnjak,ZJ;Kampine,JP
通讯作者：
Kampine,JP