Percutaneous drainage compared with surgery for hepatic hydatid cysts

Percutaneous drainage compared with surgery for hepatic hydatid cysts
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DOI:
10.1056/nejm199709253371303
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发表时间:
1997-09-25
影响因子:
158.5
通讯作者:
Jeelani, SG
Jeelani, SG
中科院分区:
医学1区
文献类型:
--
作者:
Khuroo, MS;Wani, NA;Jeelani, SG

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背景近年来经皮穿刺引流治疗包虫病肝包虫病已取得成功。我们进行了一项对照试验,比较经皮膀胱引流术与传统治疗膀胱切除术的安全性和有效性。方法在一项前瞻性研究中,我们随机分配了50例肝包虫病患者进行经皮引流治疗(25例)或膀胱切除术(25例)。经皮引流的患者给予阿苯达唑(每公斤体重每天10毫克,持续8周)。系列评估包括临床和生化检查、超声检查和包虫病抗体滴度的血清学检测。结果引流组平均(+/-SD)住院时间为4.2+/-1.5 d,手术组平均(+/-SD)住院时间为12.7+/-6.5 d (P
Background In recent years percutaneous drainage has been used successfully to treat the hepatic hydatid cysts of echinococcal disease. We performed a controlled trial to compare the safety and efficacy of percutaneous drainage with those of surgical cystectomy, the traditional treatment.Methods In a prospective study, we randomly assigned 50 patients with hepatic hydatidosis to treatment with percutaneous drainage (25 patients) or cystectomy (25). Albendazole (10 mg per kilogram of body weight per day for eight weeks) was administered to the patients who underwent percutaneous drainage. Serial assessments included clinical and biochemical examinations, ultrasonography, and serologic tests of echinococcal-antibody titers.Results The mean (+/-SD) hospital stay was 4.2+/-1.5 days in the drainage group and 12.7+/-6.5 days in the surgery group (P