Comparison of digito-palmar dermatoglyphic traits in children with cerebral palsy and their close family members.
Comparison of digito-palmar dermatoglyphic traits in children with cerebral palsy and their close family members.
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脑瘫患儿及其近亲属的指掌皮纹特征比较。
DOI：
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发表时间：
2009
影响因子：
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通讯作者：
Svetislav Polovina
中科院分区：
文献类型：
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作者：
Tajana Polovina;J. Miličić;M. Cvjetičanin;A. Polovina;Svetislav Polovina
脑性瘫痪是导致儿童严重残疾的主要原因之一。60名儿童(30名男孩和30名女孩)参加了这项研究。对指掌定量皮纹性状进行分析。从儿童的父母(60名母亲和60名父亲)和来自萨格勒布器皿的400名表型健康的成年人(作为对照组)获得指掌皮纹的指纹。对指掌复合体的数量皮纹特征的分析表明，患脑瘫的父亲和他们的孩子在许多变量上存在统计学上的差异(TRC180.3和158.6)，其中患有脑瘫的男性儿童涉及的变量更多。一些变量在父亲和健康男性对照组之间以及脑性瘫痪男孩和健康对照组男性之间显示出统计上的显著差异。患有脑瘫的母亲和女孩之间以及母亲和健康对照女性之间的皮纹模式差异显著较低(Trc 152.1和152.3)。研究结果支持这一假设，即遗传易感性在中枢神经系统损害的发生中可能起到的作用，对父亲的影响更明显。
Cerebral palsy is one of the main causes of severe disability in children. Sixty children (30 boys and 30 girls) were included in the study. Quantitative digito-palmar dermatoglyphic traits were analyzed. Prints of digito-palmar dermatoglyphs obtained from the children's parents (60 mothers and 60 fathers) and from 400 phenotypically healthy adults from the Zagreb ware used as control groups. Analysis of quantitative dermatoglyphic traits of the digito-palmar complex revealed statistically significant differences in a number of variables between the fathers and their children suffering from cerebral palsy (TRC 180.3 > 158.6), with a greater number of variables involved in male children with cerebral palsy. Some variables showed statistically significant differences in dermatoglyphic patterns between fathers and control group of healthy males as well as between boys with cerebral palsy and healthy control males. Differences in dermatoglyphic patterns were significantly lower between mothers and girls with cerebral palsy (TRC 152.1 < 152.3) as well as between mothers and healthy control females. Study results support the hypothesis on the possible role of genetic predisposition in the occurrence of central nervous system lesion, with a more pronounced paternal impact.