ENDOSCOPIC ND-YAG LASER THERAPY FOR ACTIVE ESOPHAGEAL VARICEAL BLEEDING - A RANDOMIZED CONTROLLED-STUDY
ENDOSCOPIC ND-YAG LASER THERAPY FOR ACTIVE ESOPHAGEAL VARICEAL BLEEDING - A RANDOMIZED CONTROLLED-STUDY
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DOI：
10.1016/s0016-5107(85)71954-2
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发表时间：
1985-01-01
影响因子：
7.7
通讯作者：
FLEISCHER, D
中科院分区：
文献类型：
--
作者：
FLEISCHER, D
一项随机对照双盲研究评估内镜下钕钇铝石榴石（Nd:YAG）激光治疗活动性食管静脉曲张出血的疗效和安全性。10例患者随机分为激光治疗组和对照组，对照组接受假内窥镜检查和标准药物治疗。7例激光治疗患者实现了初步止血，0例对照组接受假治疗（P < 0.002）。最初接受激光治疗的7人中有4人在12-48小时后再次出血；10例激光患者中3例持久止血。两组患者的平均输血需血量相似（激光= 7.3 U，对照组= 7.8 U）。10名接受激光治疗的患者中有6人出院，4人死亡。对照组住院死亡7例，出院3例（P = 0.22）。治疗组2例患者，激光治疗增加出血。没有穿孔。
A randomized controlled double-blind study was undertaken to assess the efficacy and safety of endoscopic neodymium:yttrium aluminum garnet (Nd:YAG) laser therapy for active esophageal variceal bleeding. Ten patients were randomized to the laser treatment group and 10 to a control group that received sham endoscopy and standard medical therapy. Initial hemostasis was achieved in 7 laser-treated patients and in 0 controls receiving sham treatment (P < 0.002). Four of the 7 who were initially controlled with laser therapy had rebleeding 12-48 h later; 3 of 10 laser patients had lasting hemostasis. The mean blood transfusion requirements were similar in both groups (laser = 7.3 U; control = 7.8 U). Six of the 10 laser-treated patients were discharged from the hospital and 4 died. There were 7 hospital deaths in the control group and 3 patients were discharged (P = 0.22). In 2 patients in the treatment group, laser therapy increased bleeding. There were no perforations.