Foetal testosterone, social relationships, and restricted interests in children

Foetal testosterone, social relationships, and restricted interests in children
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DOI:
10.1111/j.1469-7610.2004.00349.x
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发表时间:
2005-02-01
影响因子:
7.6
通讯作者:
Taylor, K
Taylor, K
中科院分区:
医学1区
文献类型:
--
作者:
Knickmeyer, R;Baron-Cohen, S;Taylor, K

文献摘要

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背景:性别差异存在于人类社会行为的某些领域。在动物中,胎儿睾丸激素(fT)在组织大脑和后来的社会行为中起着核心作用。fT还与人类的语言发展、目光接触和空间能力有关。方法:对58例儿童(男35例,女23例)在4岁时进行羊水fT分析。他们的母亲完成了儿童沟通检查表,这是一份评估语言、社会关系质量和限制兴趣的问卷。结果:考虑到性别差异,fT与社会关系质量呈负相关。fT还与男孩的兴趣限制呈正相关。结论:这些发现暗示fT在社会发展和注意力集中方面都有影响。它们也可能对理解自闭症的性别比例有启示。
Background: Sex-differences exist in some areas of human social behaviour. In animals, foetal testosterone (fT) plays a central role in organising the brain and in later social behaviour. fT has also been implicated in language development, eye-contact, and spatial ability in humans. Methods: Fifty-eight children (35 male and 23 female), whose fT was analysed in amniotic fluid, were followed up at age 4. Their mothers completed the Children's Communication Checklist, a questionnaire assessing language, quality of social relationships and restricted interests. Results: fT was negatively correlated to quality of social relationships, taking sex-differences into account. fT was also positively correlated with restricted interests in boys. Conclusions: These findings implicate fT in both social development and attentional focus. They may also have implications for understanding the sex ratio in autism.