Simultaneous Infection of the Skin Surface and Dermal Tissue with Two Different Fungus Mimicking Pyoderma Gangrenosum: A Case Report.
Simultaneous Infection of the Skin Surface and Dermal Tissue with Two Different Fungus Mimicking Pyoderma Gangrenosum: A Case Report.
复制标题
两种不同的模拟坏疽性脓皮病的真菌同时感染皮肤表面和真皮组织：一例报告
DOI：
10.2147/ccid.s286582
复制
发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Li HM
中科院分区：
文献类型：
--
作者：
Jia QY;Song YG;Li XQ;Mu ZL;Li RY;Li HM
摘要毛霉菌病是由毛霉亚门真菌引起的一种机会性真菌感染。皮肤毛霉菌病是毛霉菌病的第三种最常见表现，其特征性表现是迅速演变为坏死的硬化斑块。红色毛癣菌是最常见的皮肤癣菌之一，主要引起浅表感染，很少引起深部感染。本文报告一个皮肤真菌感染的病例，其中分离出两种真菌，且皮肤损害类似坏疽性脓疡。从痂皮中分离出红色毛癣菌，在皮肤组织中发现毛霉亚门的菌丝。不规则的全身和局部使用类固醇治疗是混合真菌感染的可能原因，在这个病人，建议定期类固醇治疗的重要性。
Abstract Mucormycosis is an opportunistic fungal infection driven by subphylum Mucormycotina. Cutaneous mucormycosis is the third most common presentation of mucormycosis, and its characterized presentation is an indurated plaque that rapidly evolves to necrosis. Trichophyton rubrum is one of the most common dermatophytes that mainly cause superficial infections and seldom induce deep infections. The present report presents a case of cutaneous fungal infection, in which two kinds of fungus were isolated, and the skin lesion mimicked pyoderma gangrenosum. Trichophyton rubrum was isolated from the crust and hyphae of subphylum Mucormycotina were found in dermal tissue. The irregular systemic and topical use of steroid therapy is the possible cause of the mixed fungal infection in this patient, suggesting the importance of regular steroid therapy.