Study of the mucosal immune response duration in mice after administration of a candidate edible vaccine based on transgenic tomato plants carrying the TBI-HBS gene

Study of the mucosal immune response duration in mice after administration of a candidate edible vaccine based on transgenic tomato plants carrying the TBI-HBS gene
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基于携带 TBI-HBS 基因的转基因番茄植物的候选食用疫苗施用后小鼠粘膜免疫反应持续时间的研究

DOI:
10.1134/s1607672909050020
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发表时间:
2009
影响因子:
0.8
通讯作者:
R. Hammond
R. Hammond
中科院分区:
生物学4区
文献类型:
--
作者:
R. K. Salyaev;N. Rekoslavskaya;S. Shchelkunov;A. Stolbikov;R. Hammond

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粘膜免疫系统是胃肠道、呼吸道和泌尿生殖道的所有粘液组织的整体表面。粘膜免疫系统的最佳研究组成部分是胃肠道,其含有派尔氏斑,其表皮富含M细胞。后者接受抗原并将其运输到下面的滤泡,在那里产生T和B细胞免疫应答。
The mucosal immune system is the overall surface of all mucous tissues of the gastrointestinal, respira tory, and urogenital tracts. The best studied compo nent of the mucosal immune system is the gastrointes tinal tract, which contains Peyers plaques, whose epi thelium is enriched in M cells. The latter accept antigens and transport them to the underlying folli cles, where T and B cell immune responses develop.
DOI: 10.1073/pnas.0510843103
发表时间: 2006-05
影响因子: 11.1
作者:
Sharon X Wen;L. Teel;Nicole A. Judge;A. O’Brien
通讯作者: Sharon X Wen;L. Teel;Nicole A. Judge;A. O’Brien