Normal ranges and test-retest reproducibility of flow and velocity parameters in intracranial arteries measured with phase-contrast magnetic resonance imaging
Normal ranges and test-retest reproducibility of flow and velocity parameters in intracranial arteries measured with phase-contrast magnetic resonance imaging
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DOI：
10.1007/s00234-016-1661-6
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发表时间：
2016-05-01
期刊：
影响因子：
2.8
通讯作者：
Wikstrom, Johan
中科院分区：
文献类型：
--
作者：
de Verdier, Maria Correia;Wikstrom, Johan
本研究的目的是探讨相衬MRI （PC-MRI）测量颅内动脉血流和速度参数的正常范围和测试-重测的重复性。方法30例健康志愿者在3 t时使用二维PC-MRI分别测量大脑前动脉（ACA）、中动脉（MCA）和后动脉（PCA）的最高血流（HF）、最低血流（LF）、峰值收缩速度（PSV）和舒张末期血流（EDV）。结果左心房HF(平均（范围，LDD） 126 ml/min (36 ~ 312,59 %), LF 61 ml/min (0 ~ 156,101%), PSV 64 cm/s (32 ~ 141,67 %), EDV 35 cm/s (18 ~ 55,42 %)；在右侧ACA中，HF为154 ml/min (42- 246.49%)， LF为77 ml/min (0- 156.131%)， PSV为75 cm/s (26- 166.82%)， EDV为39 cm/s（7- 59.67%）。左中动脉HF为235 ml/min (126- 372,35 %)， LF为116 ml/min (42- 186,48 %)， PSV为90 cm/s (55- 183,39 %)， EDV为46 cm/s (20- 66,28 %)；右中动脉HF 238 ml/min (162- 342,44 %), LF 120 ml/min (72- 216,48 %), PSV 88 cm/s (55- 141,35 %), EDV 45 cm/s（26- 67,23 %）。左侧PCA中，HF为108 ml/min (42- 168.54 %)， LF为53 ml/min (18- 108.64 %)， PSV为50 cm/s (24- 77.63 %)， EDV为28 cm/s (14- 404.45 %)；在右侧PCA中，HF为98 ml/min (30- 162.49%)， LF为49 ml/min (12- 84.55%)， PSV为47 cm/s (27- 88.59%)， EDV为27 cm/s（16- 41.45%）。结论pc - mri测量颅内主要动脉血流、速度参数范围大，正常范围广。MCA重现性最高。
Introduction The purpose of the present study was to investigate normal ranges and test-retest reproducibility of phase-contrast MRI (PC-MRI)-measured flow and velocity parameters in intracranial arteries.Methods Highest flow (HF), lowest flow (LF), peak systolic velocity (PSV), and end diastolic velocity (EDV) were measured at two dates in the anterior (ACA), middle (MCA), and posterior (PCA) cerebral arteries of 30 healthy volunteers using two-dimensional PC-MRI at 3 T. Least detectable difference (LDD) was calculated.Results In the left ACA, HF was (mean (range, LDD)) 126 ml/min (36-312, 59 %), LF 61 ml/min (0-156, 101 %), PSV 64 cm/s (32-141, 67 %), and EDV 35 cm/s (18-55, 42 %); in the right ACA, HF was 154 ml/min (42-246, 49 %), LF 77 ml/min (0-156, 131 %), PSV 75 cm/s (26-161, 82 %), and EDV 39 cm/s (7-59, 67 %). In the left MCA, HF was 235 ml/min (126-372, 35 %), LF 116 ml/min (42-186, 48 %), PSV 90 cm/s (55-183, 39 %), and EDV 46 cm/s (20-66, 28 %); in the right MCA, HF was 238 ml/min (162-342, 44 %), LF 120 ml/min (72-216, 48 %), PSV 88 cm/s (55-141, 35 %), and EDV 45 cm/s (26-67, 23 %). In the left PCA, HF was 108 ml/min (42-168, 54 %), LF 53 ml/min (18-108, 64 %), PSV 50 cm/s (24-77, 63 %), and EDV 28 cm/s (14-40, 45 %); in the right PCA, HF was 98 ml/min (30-162, 49 %), LF 49 ml/min (12-84, 55 %), PSV 47 cm/s (27-88, 59 %), and EDV 27 cm/s (16-41, 45 %).Conclusion PC-MRI-measured flow and velocity parameters in the main intracranial arteries have large normal ranges. Reproducibility is highest in MCA.