Blood coagulation in hemophilia A and hemophilia C
Blood coagulation in hemophilia A and hemophilia C
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DOI：
10.1182/blood.v91.12.4581.412k12_4581_4592
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发表时间：
1998-06-15
期刊：
影响因子：
20.3
通讯作者：
Mann, KG
中科院分区：
文献类型：
--
作者：
Cawthern, KM;van't Veer, C;Mann, KG
在正常、VIII因子缺乏和XI因子缺乏供体的接触途径抑制的人血液中比较了组织因子（TF）诱导的凝血。通过免疫测定法和免疫印迹法对纤维蛋白肽A（FPA）、凝血酶-抗凝血酶（达特）、因子V活化和骨连接素的淬灭样品中的反应进程进行分析。在血友病A血液中（因子VIII：C
Tissue factor (TF)-induced coagulation was compared in contact pathway suppressed human blood from normal, factor VIII-deficient, and factor XI-deficient donors. The progress of the reaction was analyzed in quenched samples by immunoassay and immunoblotting for fibrinopeptide A (FPA), thrombin-antithrombin (TAT), factor V activation, and osteonectin. In hemophilia A blood (factor VIII:C