vSPACE: Exploring Virtual Spatial Representation of Articular Chondrocytes at the Single-Cell Level.
vSPACE: Exploring Virtual Spatial Representation of Articular Chondrocytes at the Single-Cell Level.
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vSPACE：探索单细胞水平的关节软骨细胞的虚拟空间表示。
DOI：
10.1101/2024.02.07.577817
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发表时间：
2024
期刊：
影响因子：
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通讯作者：
Shin,Dong-Guk
中科院分区：
文献类型：
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作者：
Zhang,Chenyu;Wang,Honglin;Hong,Seung-Hyun;Olmer,Merissa;Swahn,Hannah;Lotz,MartinK;Maye,Peter;Rowe,David;Shin,Dong-Guk
摘要vSPACE是一个基于Web的应用程序，通过模仿空间转录组学技术的概念，呈现从人类关节软骨获得的scRNAseq数据的空间表示，但虚拟。这种对人类关节软骨细胞的虚拟2D绘图演示一次为一个或多个基因生成几个带状分布模式，揭示了科学家可以理解的模式，作为沿带状轴的推测空间分布模式。vSPACE作为一个基于Web的工具箱在Python Dash中实现，旨在对关节软骨细胞中的带状基因表达模式进行数据可视化。此工具可免费访问：https://vspace.cse.uconn.edu/The源代码，有关此服务的额外材料可从以下地址下载：https://github.com/zhacheny/vSPACE
SummaryvSPACE is a web-based application presenting a spatial representation of scRNAseq data obtained from human articular cartilage by emulating the concept of spatial transcriptomics technology, but virtually. This virtual 2D plot presentation of human articular cartage cells generates several zonal distribution patterns, for one or multiple genes at a time, revealing patterns that scientists can appreciate as imputed spatial distribution patterns along the zonal axis.Availability and implementationvSPACE is implemented in Python Dash as a web-based toolbox designed for data visualization of zonal gene expression patterns in articular cartilage chondrocytes. This tool is freely accessible at: https://vspace.cse.uconn.edu/The source code and extra materials for this service can be downloaded from: https://github.com/zhacheny/vSPACE