Co-assembly behaviour of Janus nanoparticles and amphiphilic block copolymers in dilute solution.
Co-assembly behaviour of Janus nanoparticles and amphiphilic block copolymers in dilute solution.
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DOI：
10.1039/c7cp04501h
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发表时间：
2017-09
期刊：
影响因子：
--
通讯作者：
Qing Li;Liquan Wang;Jiaping Lin
中科院分区：
文献类型：
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作者：
Qing Li;Liquan Wang;Jiaping Lin
纳米粒子可以与两亲性嵌段共聚物（ABPs）在溶液中共组装以产生具有独特性质的纳米聚集体，然而Janus纳米粒子（JPs）和ABPs的这种共组装行为的机制仍不清楚。在这里，JP/ABP混合物在稀溶液中的自组装行为进行了研究，通过理论模拟。考虑了两种不同亲水嵌段体积分数fA的ABPs：一种是fA = 0.5的对称共聚物，另一种是fA = 0.3的不对称ABPs。在第一种情况下，随着纳米颗粒体积分数cJP的增加，依次形成球和棒，连接网络和囊泡的混合物。在第二种情况下，囊泡不断形成。对于这两种情况，在较低的cJP值，纳米颗粒位于芯-冠界面。相比之下，在较高的颗粒负载量，大量的颗粒参与嵌入囊泡壁中的簇。基于模拟结果，构建了cJP和fA空间中的形态图，以指示不同纳米结构的稳定区域。具体地，发现由具有短亲水性嵌段的JP和ABP形成的囊泡是刺激响应性的。通过改变疏水嵌段之间的相互作用参数，可以在囊泡壁中产生可控的孔。我们的研究结果不仅提供了对Janus纳米颗粒和两亲性嵌段共聚物在溶液中的共组装行为的见解，而且还提供了一种制备具有渗透膜的纳米反应器的新策略。
Nanoparticles can co-assemble with amphiphilic block copolymers (ABPs) in solution to generate nanoaggregates with unique properties, yet the mechanism of such a co-assembly behaviour for Janus nanoparticles (JPs) and ABPs remains unclear. Here, the self-assembly behaviour of JP/ABP mixtures in dilute solution was studied via theoretical simulations. Two kinds of ABPs with different volume fractions fA of hydrophilic blocks were considered: one is symmetric copolymers with fA = 0.5, and the other is asymmetric ABPs with fA = 0.3. In the first case, mixtures of spheres and rods, connected networks and vesicles were formed sequentially as the volume fraction cJP of nanoparticles increases. In the second case, vesicles were constantly formed. For both cases, at lower cJP values, the nanoparticles were located at the core-corona interfaces. By contrast, at higher particle loadings, a large number of particles were involved in clusters embedded in the vesicle walls. Based on the simulation results, a morphological diagram in the space of cJP and fA was constructed to indicate the stability regions of different nanostructures. Specifically, it was found that the vesicles formed by JPs and ABPs with short hydrophilic blocks are stimuli-responsive. By changing the interaction parameters between hydrophobic blocks, controllable pores in the vesicle walls could be created. Our findings not only provide insights into the co-assembly behaviour of Janus nanoparticles and amphiphilic block copolymers in solution, but also offer a novel strategy to prepare nanoreactors with permeable membranes.