Multi-component self-assembled anti-tumor nano-vaccines based on MUC1 glycopeptides
Multi-component self-assembled anti-tumor nano-vaccines based on MUC1 glycopeptides
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基于MUC1糖肽的多组分自组装抗肿瘤纳米疫苗
DOI：
10.1039/c6cc02000c
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发表时间：
2016-01-01
影响因子：
4.9
通讯作者：
Li, Y. M.
中科院分区：
文献类型：
--
作者：
Sun, Z. Y.;Chen, P. G.;Li, Y. M.
首次研制出同时含有Pam(3)、CSK(4)和CpG的新型多组分自组装纳米疫苗。这些多组分疫苗在体外能有效地激活巨噬细胞，在体内能诱导出较强的抗体免疫应答和抗肿瘤免疫应答。
Novel multi-component self-assembled nano-vaccines containing both Pam(3)CSK(4) and CpG were developed for the first time. These multi-component vaccines could effectively activate the macrophages in vitro and elicit strong antibody immune responses and anti-tumor immune responses in vivo.