Beyond Abdominal Pain: Pain Beliefs, Pain Affect, and Distress as Determinants of Quality of Life in Patients With Chronic Pancreatitis.
Beyond Abdominal Pain: Pain Beliefs, Pain Affect, and Distress as Determinants of Quality of Life in Patients With Chronic Pancreatitis.
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DOI：
10.1097/mcg.0000000000000922
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发表时间：
2018-07
影响因子：
2.9
通讯作者：
Lackner JM
中科院分区：
文献类型：
--
作者：
Keller CE;Wilcox CM;Gudleski GD;Branham S;Lackner JM
评估慢性胰腺炎患者疼痛、心理过程和生活质量之间的关系。慢性胰腺炎是胰腺的一种进行性炎症性疾病，其特征是导致腹痛和影响生活质量。慢性胰腺炎引起的疼痛人们知之甚少，而且常常难以治疗。这种疼痛历来被认为是起源于胰腺本身的外周过程，但越来越多的文献揭示了中心影响所起的重要作用。从疾病的生物心理社会模型的角度来看，认知变量强烈影响生活质量。然而，对影响慢性胰腺炎患者生活质量的变量了解甚少。阿拉巴马大学伯明翰分校的慢性胰腺炎患者接受了一项165个问题的测试，包括评估疼痛信念、疾病特异性生活质量、心理困扰、疼痛感觉、疼痛影响和长期痛苦的问卷调查。68名受试者在2011年2月28日至2014年1月16日期间完成了问卷调查。几乎所有（91.2%）报告服用止痛药。生活质量与报告的疼痛强度水平（r = - 0.52, p < 0.01）以及自责感显著相关。慢性胰腺炎患者生活质量损害的重要预测因子是疼痛强度和疼痛自责感。需要进一步的研究来阐明这种关系，同时评估系统修改这些变量以改善慢性胰腺炎患者的疼痛和生活质量的有效性。
To assess the relationship between pain, psychological processes and quality of life in chronic pancreatitis. Chronic pancreatitis is a progressive inflammatory disorder of the pancreas characteristically resulting in abdominal pain and impairing quality of life. Pain due to chronic pancreatitis is poorly understood and frequently difficult to treat. This pain has historically been understood as a peripheral process originating from the pancreas itself, but a growing body of literature is revealing an important role offered by central influences. Viewed through the perspective of the biopsychosocial model of illness, cognitive variables strongly influence quality of life. However, there is little understanding of variables that influence quality of life in chronic pancreatitis. Patients with chronic pancreatitis from the University of Alabama at Birmingham were administered a 165-question test battery which was comprised of questionnaires evaluating pain beliefs, disease-specific quality of life, psychological distress, pain sensation, pain affect, and long-term suffering. Sixty-eight subjects completed the question battery between 2/28/2011 and 1/16/2014. Almost all (91.2%) reported taking pain medication. Quality of life was significantly associated with reported levels of pain intensity (r = -.52, p < .01) as well as perceived self-blame. The significant predictors of quality of life impairment in chronic pancreatitis are pain intensity and perceived self-blame for pain. Further research is needed to elucidate this relationship while also evaluating the effectiveness of systematic modification of these variables in an attempt to improve pain and quality of life in chronic pancreatitis.