Post-Term Birth is Associated with Greater Risk of Obesity in Adolescent Males
Post-Term Birth is Associated with Greater Risk of Obesity in Adolescent Males
复制标题
DOI：
10.1016/j.jpeds.2011.10.030
复制
发表时间：
2012-05-01
影响因子：
5.1
通讯作者：
Cutfield, Wayne S.
中科院分区：
文献类型：
--
作者：
Beltrand, Jacques;Soboleva, Tanya K.;Cutfield, Wayne S.
目的探讨过期妊娠（>42周妊娠）对儿童生长发育和体重增加的影响。研究设计对525名儿童（包括17名男孩和20名女孩）从出生到16岁进行随访。结果出生时，足月女孩比足月女孩苗条（体重指数27.7 +/- 2.6 kg/m3 vs 26.3 +/- 2.8 kg/m3; P <0.05）。在16岁时，足月男孩比足月受试者重11.8 kg（体重指数[BMI]，25.4 +/- 5.5 kg/m2 vs 21.7 +/- 3.1 kg/m2; P <0.01）。足月儿肥胖率为29%，足月儿为7%（P < .01），超重和肥胖合并率为47%，足月儿为13%（P < .01）。在1.5-7岁（P <0.05）和11.5-16岁（P <0.05）时，足月后男孩的体重增长速度较高，但身高增长速度不高。在3岁时，足月后男孩的BMI较高，此后差异增加。体重指数和增长是相似的后期和长期的girls.Conclusion在这个后期出生队列，男孩，但不是女孩，表现出加速体重增加在儿童时期，导致更大的风险在青春期肥胖。（J Pediatr 2012;160：769-73）。
Objective To test the hypothesise that post-term birth (>42 weeks gestation) adversely affects longitudinal growth and weight gain throughout childhood.Study design A total of 525 children (including 17 boys and 20 girls born post-term) were followed from birth to age 16 years. Weight and height were recorded prospectively throughout childhood, and respective velocities from birth to end of puberty were calculated using a mathematical model.Results At birth, post-term girls were slimmer than term girls (ponderal index, 27.7 +/- 2.6 kg/m(3) vs 26.3 +/- 2.8 kg/m(3); P < .05). At age 16 years, post-term boys were 11.8 kg heavier than term subjects (body mass index [BMI], 25.4 +/- 5.5 kg/m(2) vs 21.7 +/- 3.1 kg/m(2); P < .01). The rate of obesity was 29% in post-term boys and 7% in term boys (P < .01), and the combined rate of overweight and obesity was 47% in post-term boys and 13% in term boys (P < .01). Weight velocity, but not height velocity, was higher in post-term boys at age 1.5-7 years (P < .05) and again at age 11.5-16 years (P < .05). BMI was higher in post-term boys at age 3 years, with the difference increasing thereafter. BMI and growth were similar in post-term and term girls.Conclusion In this post-term birth cohort, boys, but not girls, demonstrated accelerated weight gain during childhood, leading to greater risk of obesity in adolescence. (J Pediatr 2012;160:769-73).