Relation of coronary calcium score by electron beam computed tomography to arteriographic findings in asymptomatic and symptomatic adults
Relation of coronary calcium score by electron beam computed tomography to arteriographic findings in asymptomatic and symptomatic adults
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DOI：
10.1016/s0002-9149(96)00698-4
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发表时间：
1997-01-15
影响因子：
2.8
通讯作者：
Vizza, RF
中科院分区：
文献类型：
--
作者：
Guerci, AD;Spadaro, LA;Vizza, RF
对18名冠状动脉钙化积分升高的无症状、表面健康的成年人进行冠状动脉造影。为了将观察范围扩展至低钙评分的受试者，还分析了18例劳力性呼吸困难和/或瓣膜性心脏病和低钙评分患者的动脉造影;从冠状动脉疾病（CAD）的角度来看，这18例患者被认为是无症状的。为进行有症状和无症状受试者的比较，在最初的18例无症状受试者中，每例也选择了3例年龄和性别匹配的有症状患者。在不了解钙化评分或任何其他患者特征的情况下，在ct远程站点通过计算机辅助定量冠状动脉造影术分析动脉造影。在18例钙评分升高的无症状受试者中，平均钙评分为573 +/- 504（Agatston方法），平均最严重狭窄为45% +/-16%。对于所有36例无CAD症状的患者，最严重的狭窄与钙评分的平方根密切相关（r = 0.85，p
Coronary arteriography was performed on 18 asymptomatic, apparently healthy adults with elevated coronary calcium scores. To extend the range of observation to subjects with tow calcium scores, arteriograms from 18 patients with exertional dyspnea and/or valvular heart disease and low calcium scores were also analyzed; these 18 patients were considered asymptomatic from the point of view of coronary artery disease (CAD). For the comparison of symptomatic and asymptomatic persons, 3 age and sex-matched symptomatic patients were also selected for each of the original 18 asymptomatic subjects. Arteriograms were analyzed by computer-assisted quantitative coronary arteriography at ct remote site without knowledge of the calcium score or any other patient characteristics. In the 18 asymptomatic subjects with elevated calcium scores, the mean calcium score was 573 +/- 504 (Agatston method) and the mean worst stenosis was 45% +/- 16%. For all 36 patients without symptoms of CAD, worst stenosis was closely correlated with the square root of the calcium score (r = 0.85, p