Hammersmith Infant Neurological Examination Asymmetry Score Distinguishes Hemiplegic Cerebral Palsy From Typical Development.
Hammersmith Infant Neurological Examination Asymmetry Score Distinguishes Hemiplegic Cerebral Palsy From Typical Development.
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DOI：
10.1016/j.pediatrneurol.2018.07.002
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发表时间：
2018-10
影响因子：
3.8
通讯作者：
NCH Early Developmental Group
中科院分区：
文献类型：
--
作者：
Hay K;Nelin M;Carey H;Chorna O;Moore-Clingenpeel Ma Mas M;Maitre N;NCH Early Developmental Group
Hammersmith婴儿神经系统检查（HINE）是早期识别脑瘫（CP）的几种有用工具之一，然而，CP的截止评分并不能始终区分偏瘫婴儿和正常婴儿。我们假设，使用不对称评分，除了评估的标准总截断分数可以在临床环境中解决这个问题。这项对新生儿重症监护随访计划的回顾性研究，采用HINE的一致临床使用，将诊断为CP的婴儿与无运动延迟或神经发育障碍证据的婴儿相匹配。各组在HINE评估时具有相同的矫正胎龄和胎龄。记录了不对称存在。74例脑瘫患儿中四肢瘫28例，双瘫11例，偏瘫35例。偏瘫的中位总HINE和不对称评分分别为57.5和10，而无CP的患者为76和0。结合HINE总分5分区分偏瘫与典型发展的敏感性和特异性<63 and an asymmetry score >分别为91.8和100%。在临床环境中，结合总HINE和不对称评分可以帮助供应商区分偏瘫婴儿和那些典型的发展。
The Hammersmith Infant Neurological Examination (HINE) is one of several useful tools for early identification of Cerebral Palsy (CP), however, cut-off scores for CP do not consistently distinguish infants with hemiplegia from those typically developing. We hypothesized that use of an asymmetry score, in addition to the assessment’s standard total cut-off score could remedy this problem in a clinical setting. This retrospective study of a neonatal intensive care follow-up program with consistent clinical use of the HINE matched infants with a diagnosis of CP to infants without motor delays or evidence of neurodevelopmental impairments. Groups had same corrected and gestational ages at HINE assessment. Asymmetry presence was recorded. Of 74 infants with CP, 28 had quadriplegia, 11 had diplegia and 35 had hemiplegia. Median total HINE and asymmetry scores for hemiplegia were 57.5 and 10 vs. 76 and 0 for those without CP. Sensitivity and specificity to distinguish hemiplegia from typical development by combining a total HINE score <63 and an asymmetry score >5 were 91.8 and 100% respectively. In a clinical setting, combining total HINE and asymmetry scores can help providers differentiate infants with hemiplegia from those typically developing.
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影响因子：
26.1
作者：
Novak, Iona;Morgan, Cathy;Adde, Lars;Blackman, James;Boyd, Roslyn N.;Brunstrom-Hernandez, Janice;Cioni, Giovanni;Damiano, Diane;Darrah, Johanna;Eliasson, Ann-Christin;de Vries, Linda S.;Einspieler, Christa;Fahey, Michael;Fehlings, Darcy;Ferriero, Donna M.;Fetters, Linda;Fiori, Simona;Forssberg, Hans;Gordon, Andrew M.;Greaves, Susan;Guzzetta, Andrea;Hadders-Algra, Mijna;Harbourne, Regina;Kakooza-Mwesige, Angelina;Karlsson, Petra;Krumlinde-Sundholm, Lena;Latal, Beatrice;Loughran-Fowlds, Alison;Maitre, Nathalie;McIntyre, Sarah;Noritz, Garey;Pennington, Lindsay;Romeo, Domenico M.;Shepherd, Roberta;Spittle, Alicia J.;Thornton, Marelle;Valentine, Jane;Walker, Karen;White, Robert;Badawi, Nadia
通讯作者：
Badawi, Nadia
影响因子：
3.8
作者：
Maitre, Nathalie L.;Chorna, Olena;Guzzetta, Andrea
通讯作者：
Guzzetta, Andrea
影响因子：
5.1
作者：
Haataja, L;Mercuri, E;Dubowitz, L
通讯作者：
Dubowitz, L
影响因子：
3.8
作者：
Krumlinde-Sundholm, Lena;Ek, Linda;Eliasson, Ann-Christin
通讯作者：
Eliasson, Ann-Christin
影响因子：
3.8
作者：
Eliasson, Ann-Christin;Ullenhag, Anna;Krumlinde-Sundholm, Lena
通讯作者：
Krumlinde-Sundholm, Lena