Knowledge and attitudes about treatment for hepatitis C virus infection and barriers to treatment among current injection drug users in Australia
Knowledge and attitudes about treatment for hepatitis C virus infection and barriers to treatment among current injection drug users in Australia
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DOI：
10.1086/427446
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发表时间：
2005-04-15
影响因子：
11.8
通讯作者：
Dore, GJ
中科院分区：
文献类型：
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作者：
Doab, A;Treloar, C;Dore, GJ
尽管最近丙型肝炎病毒(HCV)感染的治疗结果有所改善，但目前很少有注射吸毒者(IDU)能够获得治疗计划。我们检查了丙型肝炎病毒感染的自然病史和治疗知识，以及寻求治疗丙型肝炎病毒感染的障碍和意愿。从悉尼市中心的初级卫生机构和美沙酮诊所采集的100名自我报告丙型肝炎病毒阳性状态的当前注射吸毒者(n=100)的便利样本完成了面试者管理的问卷调查。参与者对丙型肝炎病毒感染的自然病史有合理的了解，但对丙型肝炎病毒感染的治疗知识较差。大多数人认为，作为目前的注射吸毒者是治疗的排除标准。尽管如此，70%-80%的注射吸毒者报告说，他们会考虑在澳大利亚目前的情况下进行治疗：要求肝脏活检、皮下注射、常见的不良反应和40%的疗效。美沙酮诊所的研究参与者对治疗的考虑程度更高。这些发现支持为目前的注射吸毒者制定关于治疗丙型肝炎病毒感染的具体教育计划。
Despite recent improvements in outcomes of treatment for infection with hepatitis C virus (HCV), very few current injection drug users (IDUs) have access to treatment programs. We examined the natural history of and treatment knowledge about HCV infection and barriers and willingness to seek treatment for HCV infection. A convenience sample of current IDUs (n =100) with self-reported HCV-positive status drawn from a primary health facility and methadone clinic in inner Sydney completed an interviewer-administered questionnaire. Participants had a reasonable knowledge of the natural history of HCV infection but poorer knowledge of treatment for HCV infection. Most believed that being a current IDU was an exclusion criterion for treatment. Despite this, 70%-80% of IDUs reported that they would consider treatment under current scenarios in Australia: requirement for liver biopsy, subcutaneous injections, common adverse effects, and 40% efficacy. Study participants at the methadone clinic had higher levels of consideration of treatment. These findings support the development of specific education programs regarding treatment for HCV infection for current IDUs.