Evaluation of grades 3 and 4 chondromalacia of the knee using T2*-weighted 3D gradient-echo articular cartilage imaging
Evaluation of grades 3 and 4 chondromalacia of the knee using T2*-weighted 3D gradient-echo articular cartilage imaging
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DOI：
10.1007/s002560100330
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发表时间：
2001-06-01
影响因子：
2.1
通讯作者：
Murphy, BJ
中科院分区：
文献类型：
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作者：
Murphy, BJ
目标。目的：探讨T2加权三维(3D)梯度回波关节软骨成像对膝关节3、4级软骨病诊断的准确性。对80例同时接受关节镜检查和核磁共振检查的患者进行了回顾性评估。3D图像由一名观察者在不知道手术结果的情况下进行解释。观察股骨内侧和外侧髁、胫骨内侧和外侧平台、髌骨软骨和滑车沟。如果存在局灶性软骨厚度减少(3级软骨软化)或软骨完全丧失(4级软骨软化)，则认为MR软骨图像为阳性。将3D MR结果与关节镜检查结果进行比较。80例患者纳入研究组。共480个关节软骨部位进行了MRI和关节镜检查。MR对3、4级软化症诊断的敏感性83%，特异性97%，假阴性率17%，假阳性率3%，阳性预测值87%，阴性预测值95%，总体准确率93%。结果表明，T2加权三维梯度回波关节软骨成像可以识别膝关节3级和4级软骨软化。
Objective. To determine the accuracy of T2*-weighted three-dimensional (3D) gradient-echo articular cartilage imaging in the identification of grades 3 and 4 chondromalacia of the knee.Design and patients. A retrospective evaluation of 80 atients who underwent both arthroscopic and MRI evaluation was performed. The 3D images were interpreted by one observer without knowledge of the surgical results. The medial and lateral femoral condyles, the medial and lateral tibial plateau, the patellar cartilage and trochlear groove were evaluated. MR cartilage images were considered positive if focal reduction of cartilage thickness was present (grade 3 chondromalacia) or if complete loss of cartilage was present (grade 4 chondromalacia). Comparison of the 3D MR results with the arthroscopic findings was performed.Results. Eighty patients were included in the study group. A total of 480 articular cartilage sites were evaluated with MRI and arthroscopy. Results of MR identification of grades 3 and 4 chondromalacia, all sites combined, were: sensitivity 83%, specificity 97%, false negative rate 17%, false positive rate 3%, positive predictive value 87%, negative predictive value 95%, overall accuracy 93%.Conclusion. The results demonstrate that T2*-weighted 3D gradient-echo articular cartilage imaging can identify grades 3 and 4 chondromalacia of the knee.