Transcatheter arterial embolization of unresectable renal cell carcinoma with a mixture of ethanol and iodized oil
Transcatheter arterial embolization of unresectable renal cell carcinoma with a mixture of ethanol and iodized oil
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乙醇和碘油混合物经导管动脉栓塞治疗不可切除的肾细胞癌
DOI：
10.1007/bf00203951
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发表时间：
1994
影响因子：
2.9
通讯作者：
M. Han
中科院分区：
文献类型：
--
作者：
Jae Hyung Park;S. H. Kim;J. Han;J. Chung;M. Han
目的回顾性分析27例不能手术切除的肾癌患者经导管肾动脉栓塞（TAE）的疗效。方法采用10-28 ml的无水乙醇和碘化油（3 ∶ 1）混合栓塞剂，对症状缓解或永久性缓解的肾癌患者行TAE，以达到完全或部分消融的目的。分析了临床、血管造影和计算机断层扫描（CT）随访。累积生存率估计与Kaplan-Meier法。ResultsPartial（5）或complete（22）消融栓塞肾在所有情况下实现。1个月后的随访CT显示肿瘤区域碘油摄取（14/14）、肿瘤尺寸缩小（6/14）和气体形成（7/14）。1例肺转移瘤患者经动脉栓塞和持续化疗后明显好转。27例患者的总中位生存期为8.5个月。中位生存期为23个月，10例III期，其中3人仍然活着，和7个月，15例IV期tumors.ConclusionThe乙醇和碘油的混合物不仅是一种方便的栓塞材料使用，但也是有效的选择性或非选择性断流术不可切除的肾细胞癌。
PurposeThe effectiveness of renal transcatheter arterial embolization (TAE) with a mixture of ethanol and iodized oil (Lipiodol) was analyzed retrospectively in 27 patients with unresectable renal cell carcinoma.MethodsSymptomatic or permanent palliation by TAE was performed with the intent to achieve total or partial ablation of the kidney with 10–28 ml of embolic material in a 3 ∶ 1 mixture of ethanol and iodized oil. Clinical, angiographic, and computed tomographic (CT) follow-up were analyzed. Cumulative survival was estimated with the Kaplan-Meier method.ResultsPartial (5) or complete (22) ablation of the embolized kidneys was achieved in all cases. Follow-up CT after 1 month revealed Lipiodol uptake in the tumor area (14/14), decreased size of the tumor (6/14), and gas formation (7/14). Pulmonary metastasis improved significantly in one patient after transcatheter arterial embolization and adjunctive chemotherapy. Overall median survival of the 27 patients was 8.5 months. The median survival was 23 months in 10 patients with stage III, three of whom are still alive, and was 7 months in 15 patients with stage IV tumors.ConclusionThe mixture of ethanol and Lipiodol is not only a convenient embolic material to use, but is also effective for selective or nonselective devascularization for unresectable renal cell carcinoma.
梗死肾切除术治疗转移性肾癌。
影响因子：
2.1
作者：
Gottesman,JE;Crawford,ED;Grossman,HB;Scardino,P;McCracken,JD
通讯作者：
McCracken,JD