Circadian rhythm in the cardiovascular system: Chronocardiology
Circadian rhythm in the cardiovascular system: Chronocardiology
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DOI：
10.1016/s0002-8703(02)94797-6
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发表时间：
2003-05-01
影响因子：
4.8
通讯作者：
Stein, PK
中科院分区：
文献类型：
--
作者：
Guo, YF;Stein, PK
背景我们回顾了心血管系统时间生物学方面的研究最新进展。方法以Medline为主要检索工具，获取所选论文的全文。结果共找到300多篇参考文献，其中52篇代表该领域的主要发现被纳入参考文献列表。这些研究结果证实，大多数心血管生理参数（如心率、血压、心电图指数）和病理生理事件（心肌缺血/梗死、心源性猝死）显示出昼夜节律。结果还表明，考虑这些节律对于心血管疾病的诊断和治疗很重要，并且恢复正常的昼夜节律可能与临床改善相关。 结论 心血管系统昼夜节律的研究正在成为一个重要的研究领域，因为它对患者管理具有潜在的影响。
Background We reviewed recent progress in the study of the chronobiological aspects of the cardiovascular system.Methods Medline was used as the main search tool, and the full texts of selected papers were obtained.Results More than 300 references were found, and 52 of them, representing the major findings in this field, were included in the reference list. Results of these studies confirm that most cardiovascular physiological parameters (such as heart rate, blood pressure, electrocardiogram indices) and pathophysiological events (myocardial ischemia/infarction, sudden cardiac death) show circadian rhythms. Results also suggest that consideration of these rhythms is important for the diagnosis and treatment of cardiovascular disorders and that restoration of normal circadian rhythms may be associated with clinical improvement.Conclusion The study of circadian rhythms in the cardiovascular system is emerging as an important area of investigation because of its potential implications for patient management.